Heron · National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System 2017 · National mortality surveillance report · n=?

Deaths: Leading Causes for 2015.

Cited 67 times in the scientific literature.

Level 4 - case-series / case-control

Cross-sectional national vital statistics registry analysis (graded by design analogy)

PubMed 29235984 · record verified 2026-08-30

What was done

The National Center for Health Statistics analyzed final 2015 mortality data using all death certificates filed across the 50 US states and the District of Columbia. Causes of death were classified according to ICD-10 and ranked by the number of deaths assigned to rankable causes based on the underlying cause of death, stratified by age, sex, race, Hispanic origin, and infant developmental periods (neonatal and postneonatal).

What was found

The 10 leading causes of death in the US in 2015 in rank order were: diseases of heart; malignant neoplasms; chronic lower respiratory diseases; accidents (unintentional injuries); cerebrovascular diseases; Alzheimer's disease; diabetes mellitus; influenza and pneumonia; nephritis, nephrotic syndrome and nephrosis; and intentional self-harm (suicide). Together, they accounted for 74% of all US deaths. The leading causes of infant death were led by congenital malformations/chromosomal abnormalities, disorders related to short gestation/low birth weight, and sudden infant death syndrome. Specific ranking variations were observed across demographic subgroups.

Why it matters

This report establishes the official national epidemiological benchmark for US mortality in 2015, defining the primary population-level causes of death.

Limits

The abstract provides rank orderings and one aggregate proportion (74%) but omits absolute counts, rates, and detailed subgroup metrics. Findings rely on death certificate underlying-cause-of-death reporting, which can have classification and reporting inaccuracies.

Cited by