Zhao · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 · case-control study · n=2173

Relationship Between the ABO Blood Group and the Coronavirus Disease 2019 (COVID-19) Susceptibility.

Cited 578 times in the scientific literature.

Level 4 - case-series / case-control

Case-control study comparing COVID-19 patients to local control populations

PubMed 32750119 · doi:10.1093/cid/ciaa1150 · record verified 2026-08-30

What was done

Authors compared ABO blood group distributions in 2,173 COVID-19 patients against local control populations to explore the relationship between blood group and COVID-19 susceptibility.

What was found

Blood group A was associated with an increased risk of COVID-19 infection, whereas blood group O was associated with a decreased risk. The abstract reports no numerical values, effect sizes, odds ratios, or confidence intervals.

Why it matters

This study provides observational evidence linking ABO blood group phenotype to variation in SARS-CoV-2 infection susceptibility.

Limits

The abstract provides no quantitative data or risk estimates, does not specify the sample size or source of the control population, and does not report adjustments for potential demographic or clinical confounders.

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