Tani M Linville · DigitalCommons-Cedarville (Cedarville University) 2016 · historical narrative review · n=?

Project MKULTRA and the Search for Mind Control: Clandestine Use of LSD Within the CIA

Cited 2 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Level 5 by design analogy (narrative historical review with no empirical data)

OpenAlex W2442591092 · record verified 2026-08-31

What was done

This historical paper reviews the Central Intelligence Agency's (CIA) clandestine MKULTRA program from 1953 to 1964, examining the agency's interest in LSD for offensive and defensive mind manipulation in national security and evaluating the conduct of involved personnel against prevailing ethical frameworks.

What was found

The abstract reports no numerical findings or quantitative data. It states that minimal documentation was kept on the research and concludes that intelligence agents, physicians, and researchers involved in the experiments directly violated ethical codes, including the Hippocratic Oath, the U.S. Constitution, the Nuremberg Code, and the United Nations Declaration of Human Rights.

Why it matters

It documents historical violations of bioethical standards and human rights during state-sponsored psychedelic and mind-control research.

Limits

The work is a non-empirical historical narrative without a clinical or experimental sample. The abstract notes that minimal original documentation was preserved from the research, and details regarding specific archival sources or methods are not provided.

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