HoldsUp

George Brooks

George A. Brooks, Ph.D., is a researcher in physiology and metabolism known for developing the lactate shuttle hypothesis. His published research focuses on carbohydrate and lactate kinetics, muscle fuel utilization, and mitochondrial bioenergetics in the context of exercise and aging. He also investigates the potential therapeutic applications of lactate in neurological conditions and metabolic regulation.

36 claims checked on air: 1 context 1 contradicted 1 overstated 31 supported 2 unverified 2 flagged

What they said on air - unverified

9 citing their own research

0:40:30unverifiedvery lowGeorge Brooks, Ph.D. on Lactate Shuttle Theory, Relevance fo

In isotope tracer studies, ingested lactate is absorbed by the intestinal tract and oxidized in breath within 5 minutes, compared to at least 30 minutes for ingested glucose to peak.

"And you can see the lactate is the first taken up by the intestinal tract, and it's burned and it's in the breath in five minutes. But it takes at least a half hour for glucose to get there and reach your peak." (said at 0:40:30)

No published record matching the claim that ingested isotopically labeled lactate is absorbed and detected in breath CO2 within 5 minutes, compared to at least 30 minutes for glucose to reach its peak, was located; this does not prove the claim false.

0:49:36unverifiedvery lowGeorge Brooks, Ph.D. on Lactate Shuttle Theory, Relevance fo

When humans ingest carbohydrates, whole-body lactate production increases substantially, but blood lactate only rises modestly because lactate is rapidly cleared by tissues including the heart, liver, and brain.

"And nobody actually realized this because unless you use isotope tracers like we did, you know, you eat carbohydrate and your blood lactate rises a little bit, but actually the production went way up, it just was removed by the heart, by the liver, by the brain, by all these different tissues that are using it as a source of energy." (said at 0:49:36)

No published record matching the claim that carbohydrate ingestion causes a large increase in whole-body lactate production that is masked in blood concentration by rapid clearance across tissues such as the heart, liver, and brain was located; this does not prove the claim false.

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