Georgia Ede
Dr. Georgia Ede works in the field of metabolic psychiatry. Her published research focuses on the application of ketogenic metabolic therapy and ketogenic diets for treating mental health disorders and refractory mental illness. Her work also examines the use of ketogenic diets for weight management, alongside the contraindications, side effects, and clinical best practices associated with these dietary interventions.
18 claims checked on air: 2 context 1 contradicted 5 overstated 8 supported 2 unverified
What they said on air - citing their own research
2 citing their own research
In a published study of 31 psychiatric inpatients, 28 were able to stay on a ketogenic diet for 2 weeks or longer, all 28 improved substantially, 43% achieved full clinical remission from their primary psychiatric diagnosis, and 64% were discharged on reduced psychiatric medication.
"28 of those 31 patients were able to stay on the diet for 2 weeks or longer, which is what you need to do to start to see benefits. All 28 of those patients improved substantially to the point that 43% of them achieved full clinical remission from their primary psychiatric diagnosis and 64% of them left the hospital on less psychiatric medication" (said at 0:00:00)
The speaker accurately describes the published findings of a 2022 retrospective analysis (Danan et al., 2022, co-authored by Georgia Ede) evaluating 31 psychiatric inpatients placed on an adjunctive ketogenic diet. In that study, 28 of 31 patients adhered to the diet for more than 14 days, 100% (28/28) demonstrated clinical improvement, 43% (12/28) achieved clinical remission (defined by clinical rating scales or Clinical Global Impression scores), and 64% (18/28) were discharged on reduced psychiatric medication. Because this study is an uncontrolled, retrospective chart review, the certainty of evidence for the therapeutic efficacy of the ketogenic diet in this population is very low.
- supports: The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatient… (Frontiers in psychiatry 2022) · cited 150x in the literature
"In this retrospective analysis of clinical care, 31 adults with severe, persistent mental illness (major depressive disorder, bipolar disorder, and schizoaffective disorder) whose symptoms were poorly controlled despite intensive psychiatric management were admitted to a psychiatric hospital and placed on a ketogenic diet restricted to a maximum of 20 grams of carbohydrate per day as an adjunct to conventional inpatient care... Three patients were unable to adhere to the diet for >14 days and were excluded from the final analysis. Among included participants, means and standard deviations (SDs) improved for the Hamilton Depression Rating Scale scores from 25.4 (6.3) to 7.7 (4.2), P < 0.001 and the Montgomery-Åsberg Depression Rating Scale from 29.6 (7.8) to 10.1 (6.5), P < 0.001." (abstract, methods and results, passage verified)
pubmedfull study (doi)
In a 2022 published study by Dr. Albert Danan and co-authors on 31 treatment-resistant psychiatric inpatients, 28 stayed on a ketogenic diet for 2 weeks or longer, 43% achieved full clinical remission, and 64% were discharged on less psychiatric medication.
"So this study, which I was a co-author on—this study was published in 2022. The clinical work was done by my friend and colleague Dr. Albert Danan, who is a psychiatrist who's been practicing psychiatry in Toulouse, France for more than 35 years now. And he invited 31 of his most treatment-resistant patients with major depression, bipolar disorder, and schizophrenia to come into the hospital and try a mildly ketogenic whole-foods diet under his supervision to see whether or not it would be helpful... 28 of those 31 patients were able to stay on the diet for two weeks or longer... 43% of them achieved full clinical remission from their primary psychiatric diagnosis and 64% of them left the hospital on less psychiatric medication." (said at 0:44:52)
The speaker accurately describes the findings of the 2022 retrospective study by Danan et al. (co-authored by Georgia Ede), published in Frontiers in Psychiatry. In that analysis of 31 hospitalized adults with treatment-resistant major depression, bipolar disorder, or schizoaffective disorder, 28 patients adhered to a carbohydrate-restricted ketogenic diet for at least 14 days. Among those 28 patients, 43% (12/28) achieved clinical remission (defined by clinical rating scales) and 64% (18/28) were discharged on reduced psychiatric medication dosages. Because this was an uncontrolled, retrospective chart review of clinical care rather than a randomized controlled trial, the certainty of evidence for clinical efficacy is very low.
- supports: The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatient… (Frontiers in psychiatry 2022) · cited 150x in the literature
"In this retrospective analysis of clinical care, 31 adults with severe, persistent mental illness (major depressive disorder, bipolar disorder, and schizoaffective disorder) whose symptoms were poorly controlled despite intensive psychiatric management were admitted to a psychiatric hospital and placed on a ketogenic diet restricted to a maximum of 20 grams of carbohydrate per day as an adjunct to conventional inpatient care... Three patients were unable to adhere to the diet for >14 days and were excluded from the final analysis." (abstract, methods and results, passage verified)
pubmedfull study (doi)
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