HoldsUp

Jed W. Fahey

Cullman Chemoprotection Center at Johns Hopkins

Jed W. Fahey, Sc.D., is a nutritional biochemist and director of the Cullman Chemoprotection Center at Johns Hopkins with a background in plant physiology, human nutrition, and phytochemistry. His research primarily focuses on the bioavailability and biological effects of isothiocyanates, particularly sulforaphane and glucoraphanin derived from broccoli seeds and sprouts. His published work includes clinical and laboratory studies evaluating these compounds in the contexts of metabolic health, skin disorders, autism spectrum disorder, schizophrenia, and cancer.

74 claims checked on air: 3 context 1 overstated 64 supported 6 unverified 1 flagged

What they said on air - flagged

23 citing their own research

2:18:00overstatedmoderatetheir own paperJed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Morin

A 2014 clinical study in China found that broccoli sprout extract consumption increased the urinary excretion of benzene and acrolein conjugates by 60%.

"And so the most recent of those studies we published in 2014 showed really a dramatic enhancement of the clearance of benzene and acrolein and other pollutant conjugates in lockstep with broccoli sprout extract consumption. It was a 60% increase in excretion, which is just phenomenal." (said at 2:18:00)

A 2014 randomized clinical trial in Qidong, China (n=291) tested a broccoli sprout beverage providing glucoraphanin and sulforaphane against placebo for 12 weeks. The trial found a statistically significant 61% increase in urinary excretion of benzene-derived glutathione conjugates (mercapturic acids), but the increase for acrolein conjugates was 23%, and no significant increase was observed for crotonaldehyde. Claiming a 60% increase for both benzene and acrolein overstates the effect size observed for acrolein.

Fact-checked episodes

Publications