Satchidananda Panda
Salk Institute for Biological Studies
Satchidananda Panda is a professor in the Regulatory Biology Laboratory at the Salk Institute for Biological Studies specializing in chronobiology and circadian rhythms. His research explores the genetic, genomic, and biochemical mechanisms governing biological day-night cycles, including retinal light sensing through melanopsin. His published work focuses extensively on time-restricted eating and meal timing, investigating its effects on weight loss, sleep quality, and metabolic outcomes such as glycemic control in obesity and type 2 diabetes.
38 claims checked on air: 2 context 4 contradicted 25 supported 7 unverified
What they said on air - unverified
Sitting next to a large window in the morning provides approximately 1,000 lux of daylight exposure.
"if you are sitting next to a window, large window, and having your breakfast, although you don't have sunlight falling on your eyes, you still get around 1,000 lux of daylight." (said at 0:12:40)
No published record matching the claim that sitting next to a large window during morning hours provides approximately 1,000 lux of daylight exposure was located; this does not prove the claim false.
Looking at the sky on a sunny day exposes the eyes to between 100,000 and 200,000 lux of light.
"if you are outside on a sunny day in California or a sunny day in any place, and if you're looking at the sky, not actually looking at the sun, you get somewhere between 100,000 to 200,000 lux of light." (said at 0:14:40)
No published record matching the claim that looking at the sky on a sunny day without looking directly at the sun exposes the eyes to between 100,000 and 200,000 lux was located; this does not prove the claim false.
The International Labour Organization and European definitions classify someone as a shift worker if they stay awake for 2 to 3 hours between 10:00 p.m. and 5:00 a.m. for at least 50 days in a year.
"the International Labour Organization and some of the European countries, they have come up with a working definition of shift work, which means, which essentially translates to very simple term, like if you stay awake for two to three hours between 10:00 p.m. and 5:00 a.m. for 50 days in a year—so that is, on an average, one day in a week—then you may be considered as a shift worker." (said at 0:29:45)
No published record matching the claim that the International Labour Organization and European definitions classify an individual as a shift worker if they stay awake for 2 to 3 hours between 10:00 p.m. and 5:00 a.m. for at least 50 days in a year was located; this does not prove the claim false.
The lighting industry is a $27 billion market.
"And lighting itself is a $27 billion industry" (said at 0:44:20)
No published record matching the claim that the lighting industry is a $27 billion market was located; this does not prove the claim false. Published estimates of lighting market size vary substantially depending on geographic scope, segment (e.g., fixtures, lamps, or specific technologies like LEDs), and whether lighting equipment revenue or lighting energy expenditure is evaluated.
Consuming food within an 8- to 10-hour window in mice enhances detoxification, improves substrate metabolism, enhances mitochondrial function, lowers reactive oxygen species, and boosts autophagy.
"this timed eating is triggering breakdown of toxic materials, detoxification during the fasting time, better usage of fat, protein, and carbohydrate during day and night, and improvement in metabolism and mitochondria function that reduces reactive oxygen species—all of these good things—and improved autophagy. All of these things are happening when mice eat within 8 to 10 hours." (said at 0:54:37)
No published record matching the claim that consuming food within an 8- to 10-hour window in mice enhances detoxification, substrate metabolism, mitochondrial function, reduces reactive oxygen species, and boosts autophagy was located; this does not prove the claim false.
App data shows that people are most likely to consume alcohol and sugary treats between 7:00 p.m. and 11:00 p.m. or midnight.
"For example, if you ask what time of the day people are more likely to drink alcohol and have more sugary treats, it's between 7:00 p.m. and 11:00 p.m. or midnight." (said at 1:01:37)
No published record matching the claim that smartphone app tracking data shows people are most likely to consume alcohol and sugary treats between 7:00 p.m. and 11:00 p.m. or midnight was located; this does not prove the claim false.
Restricting eating to an 8-hour window while cutting calories to around 1,000 kcal per day and doing intense exercise can adversely alter bile acid metabolism and increase kidney stone risk.
"because occasionally we do see some people try to do eight hours time-restricted eating, at the same time reducing calories to almost 1,000 kilocalories per day, and increasing the activity level, running half a marathon once a week or 5K three times a week, and that can adversely affect your body weight, can affect even your bile acid metabolism, and might increase risk for kidney stones." (said at 1:09:05)
No published record matching the claim that restricting eating to an 8-hour window combined with cutting caloric intake to around 1,000 kcal per day and performing intense exercise adversely alters bile acid metabolism and increases kidney stone risk was located; this does not prove the claim false.
Fact-checked episodes
Publications
- Neuropsin-expressing cells in the retina affect melanopsin expression and response to light in mice.Scientific reports 2026 · CEBM Level 5
- NutriRAG: unleashing the power of large language models for food identification and classification through retrieval methods.Journal of the American Medical Informatics Association : JAMIA 2026 · CEBM Level 4
- Comparison of Self-Reported Dietary Recalls and Real-Time Tools to Track Mealtimes in Older Adults: A Pilot Study.Inquiry : a journal of medical care organization, provision and financing 2026 · CEBM Level 4
- Relative Effects of Time-Restricted Eating, Energy-Restricted Eating, and Unrestricted Eating on Eating Patterns and Dietary Intake: Results From a Randomized Controlled Trial.Journal of the Academy of Nutrition and Dietetics 2026 · CEBM Level 2
- The diversity and consistency of what and when people eat.Nature metabolism 2026 · CEBM Level 4
- Retinal ganglion cells expressing melanopsin.Handbook of clinical neurology 2026 · CEBM Level 5
- Time-Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity: The TREAD Randomized Control Trial.Obesity (Silver Spring, Md.) 2026 · CEBM Level 2
- Time Restricted Feeding Mitigates High-Fat-Diet Induced Sleep Disruption and Amplifies NREM Substates.bioRxiv : the preprint server for biology 2026 · CEBM Level 5
- Relationship Between Sleep and Meal Timing with Glycemia Parameters in Individuals with Obesity Participating in a Randomized Time-Restricted Eating Study.Nutrients 2026 · CEBM Level 3
- Time-restricted eating in adults with type 2 diabetes mellitus on concomitant glucagon-like peptide-1 receptor agonists: case report.Frontiers in clinical diabetes and healthcare 2026 · CEBM Level 4
- Effects of time-restricted feeding on health outcomes: lessons from model organisms.The Proceedings of the Nutrition Society 2026 · CEBM Level 5
- Time of Day as a Biological Variable in Cardiovascular and Kidney Disease Research: A Scientific Statement From the American Heart Association.Arteriosclerosis, thrombosis, and vascular biology 2026 · CEBM Level 5
- Predictive models of post-prandial glucose response in persons with prediabetes and early onset type 2 diabetes: A pilot study.Diabetes, obesity & metabolism 2025 · CEBM Level 4
- Bile acid synthesis impedes tumor-specific T cell responses during liver cancer.Science (New York, N.Y.) 2025 · CEBM Level 5
- Protocol for a 1-year randomised, controlled, parallel group, open-label trial on the effects and feasibility of time-restricted eating in individuals with type 2 diabetes- The REStricted Eating Time in the treatment of type 2 diabetes (RESET2) trial.Diabetic medicine : a journal of the British Diabetic Association 2025 · CEBM Level 5
- Time-restricted eating, caloric reduction, and unrestricted eating effects on weight and metabolism: a randomized trial.Obesity (Silver Spring, Md.) 2025 · CEBM Level 2
- The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research.Nature metabolism 2025 · CEBM Level 5
- NutriRAG: Unleashing the Power of Large Language Models for Food Identification and Classification through Retrieval Methods.medRxiv : the preprint server for health sciences 2025 · CEBM Level 5
- Time-restricted eating to address persistent cancer-related fatigue among cancer survivors: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2025 · CEBM Level 2
- Genome-wide allele-specific expression in multi-tissue samples from healthy male baboons reveals the transcriptional complexity of mammals.Cell genomics 2025 · CEBM Level 5
- Comparing the effectiveness of calorie restriction with and without time-restricted eating on the circadian regulation of metabolism: rationale and protocol of a three-arm randomised controlled trial in adults at risk of type 2 diabetes.Nutrition research (New York, N.Y.) 2025 · CEBM Level 5
- Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression.Frontiers in pharmacology 2025 · CEBM Level 5
- Time-Restricted Eating Improves Quality of Life, Heart Rate, and Mitochondrial Function in Patients with Postural Orthostatic Tachycardia Syndrome.medRxiv : the preprint server for health sciences 2025 · CEBM Level 4
- Biological vs. Chronological Overnight Fasting: Influence of Last Evening Meal on Morning Glucose in Dysglycemia.Nutrients 2025 · CEBM Level 4
- Ketone body driven lipid remodeling supports thermogenic adaptation to fasting.bioRxiv : the preprint server for biology 2025 · CEBM Level 5
- Metatranscriptomics Uncover Diurnal Functional Shifts in Bacterial Transgenes with Profound Metabolic Effects.Cell host & microbe 2025 · CEBM Level 5
- The diversity and consistency of what and when people eat.Research square 2025 · CEBM Level 4
- Time-restricted eating improves quality of life, heart rate, and mitochondrial function in patients with postural orthostatic tachycardia syndrome. An open-label pilot study.Scientific reports 2025 · CEBM Level 4
- Take the reins: a study protocol of a randomized controlled trial testing the effects of time-restricted eating vs. nutrition control on cancer-related fatigue among survivors of hematological malignancies.BMC nutrition 2025 · CEBM Level 5
- Short-term 24h dietary recalls from observational studies cannot support claims on mortality.Diabetes & metabolic syndrome 2025 · CEBM Level 5
- Learning from circadian rhythm to transform cancer prevention, prognosis, and survivorship care.Trends in cancer 2024 · CEBM Level 5
- Neuronal reprogramming of mouse and human fibroblasts using transcription factors involved in suprachiasmatic nucleus development.iScience 2024 · CEBM Level 5
- Energy balance drives diurnal and nocturnal brain transcriptome rhythms.Cell reports 2024 · CEBM Level 5
- Effects of 3 months of 10-h per-day time-restricted eating and 3 months of follow-up on bodyweight and cardiometabolic health in Danish individuals at high risk of type 2 diabetes: the RESET single-centre, parallel, superiority, open-label, randomised controlled trial.The lancet. Healthy longevity 2024 · CEBM Level 2
- Diurnal expression of Dgat2 induced by time-restricted feeding maintains cardiac health in the Drosophila model of circadian disruption.Aging cell 2024 · CEBM Level 5
- Diet and Meal Pattern Determinants of Glucose Levels and Variability in Adults with and without Prediabetes or Early-Onset Type 2 Diabetes: A Pilot Study.Nutrients 2024 · CEBM Level 4
- International consensus on fasting terminology.Cell metabolism 2024 · CEBM Level 5
- Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice.Arteriosclerosis, thrombosis, and vascular biology 2024 · CEBM Level 5
- Increased central obesity correlates with physical activity and food processing in recently diagnosed multiple sclerosis.Multiple sclerosis and related disorders 2024 · CEBM Level 4
- Multi-organ transcriptome atlas of a mouse model of relative energy deficiency in sport.Cell metabolism 2024 · CEBM Level 5
- Time-Restricted Eating in Adults With Metabolic Syndrome : A Randomized Controlled Trial.Annals of internal medicine 2024 · CEBM Level 2
- A pre-post trial to examine biological mechanisms of the effects of time-restricted eating on symptoms and quality of life in bipolar disorder.BMC psychiatry 2024 · CEBM Level 5
- Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes.Nutrition & diabetes 2024 · CEBM Level 4
- Time-restricted eating to address persistent cancer-related fatigue among cancer survivors: A randomized controlled trial.Research square 2024 · CEBM Level 2
- Time-restricted eating alters the 24-hour profile of adipose tissue transcriptome in men with obesity.Obesity (Silver Spring, Md.) 2023 · CEBM Level 4
- The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial.Obesity (Silver Spring, Md.) 2023 · CEBM Level 2
- Predicting energy intake with an accelerometer-based intake-balance method.The British journal of nutrition 2023 · CEBM Level 2
- Daytime light exposure is a strong predictor of seasonal variation in sleep and circadian timing of university students.Journal of pineal research 2023 · CEBM Level 3
- Time-restricted eating did not alter insulin sensitivity or β-cell function in adults with obesity: A randomized pilot study.Obesity (Silver Spring, Md.) 2023 · CEBM Level 2
- Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals.Cell metabolism 2023 · CEBM Level 5
- Insulin-regulated serine and lipid metabolism drive peripheral neuropathy.Nature 2023 · CEBM Level 5
- Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients.Cell reports. Medicine 2023 · CEBM Level 4
- Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models.Nature communications 2023 · CEBM Level 5
- Targeting Energy Intake and Circadian Biology to Engage Mechanisms of Aging in Older Adults With Obesity: Calorie Restriction and Time-Restricted Eating.The journals of gerontology. Series A, Biological sciences and medical sciences 2023 · CEBM Level 5
- When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging.Cell metabolism 2023 · CEBM Level 5
- The Untapped Potential of Circadian Timing as a Variable for Discoveries and Reproducibility.Cellular and molecular gastroenterology and hepatology 2023 · CEBM Level 5
- Reciprocal regulation between the molecular clock and kidney injury.Life science alliance 2023 · CEBM Level 5
- Ultrastructure of Synaptic Connectivity within Subregions of the Suprachiasmatic Nucleus Revealed by a Genetically Encoded Tag and Serial Blockface Electron Microscopy.eNeuro 2023 · CEBM Level 5
- Eating architecture in adults at increased risk of type 2 diabetes: associations with body fat and glycaemic control.The British journal of nutrition 2022 · CEBM Level 4
- Time-restricted Eating for the Prevention and Management of Metabolic Diseases.Endocrine reviews 2022 · CEBM Level 5
- Time-restricted feeding and circadian autophagy for long life.Nature reviews. Endocrinology 2022 · CEBM Level 5
- Ocular and extraocular roles of neuropsin in vertebrates.Trends in neurosciences 2022 · CEBM Level 5
- Assessing temporal eating pattern in free living humans through the myCircadianClock app.International journal of obesity (2005) 2022 · CEBM Level 5
- Time-restricted eating improves glycemic control and dampens energy-consuming pathways in human adipose tissue.Nutrition (Burbank, Los Angeles County, Calif.) 2022 · CEBM Level 4
- Calorie and Time Restriction in Weight Loss.The New England journal of medicine 2022 · CEBM Level 5
- Revival of light signalling in the postmortem mouse and human retina.Nature 2022 · CEBM Level 5
- Associations between the timing of eating and weight-loss in calorically restricted healthy adults: Findings from the CALERIE study.Experimental gerontology 2022 · CEBM Level 3
- Aligning mealtimes to live longer.Science (New York, N.Y.) 2022 · CEBM Level 5
- Time for better time-restricted eating trials to lessen the burden of metabolic diseases.Cell reports. Medicine 2022 · CEBM Level 5
- Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome.Cell reports 2022 · CEBM Level 5
- Time-restricted eating to improve cardiometabolic health: The New York Time-Restricted EATing randomized clinical trial - Protocol overview.Contemporary clinical trials 2022 · CEBM Level 5
- Focus on diet and exercise.Cell metabolism 2022 · CEBM Level 5
- Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial.Cell metabolism 2022 · CEBM Level 2
- The impact of a self-selected time restricted eating intervention on eating patterns, sleep, and late-night eating in individuals with obesity.Frontiers in nutrition 2022 · CEBM Level 2
- Barriers to adherence in time-restricted eating clinical trials: An early preliminary review.Frontiers in nutrition 2022 · CEBM Level 5
- New Horizons: Circadian Control of Metabolism Offers Novel Insight Into the Cause and Treatment of Metabolic Diseases.The Journal of clinical endocrinology and metabolism 2021 · CEBM Level 5
- A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms.Proceedings of the National Academy of Sciences of the United States of America 2021 · CEBM Level 5
- Pilot Clinical Trial of Time-Restricted Eating in Patients with Metabolic Syndrome.Nutrients 2021 · CEBM Level 5
- A Timely Call to Arms: COVID-19, the Circadian Clock, and Critical Care.Journal of biological rhythms 2021 · CEBM Level 5
- The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults.Nutrients 2021 · CEBM Level 2
- Time-Restricted Eating for 12 Weeks Does Not Adversely Alter Bone Turnover in Overweight Adults.Nutrients 2021 · CEBM Level 2
- Time-Restricted Eating Improves Quality of Life Measures in Overweight Humans.Nutrients 2021 · CEBM Level 2
- Protocol for a randomised controlled trial on the feasibility and effects of 10-hour time-restricted eating on cardiometabolic disease risk among career firefighters doing 24-hour shift work: the Healthy Heroes Study.BMJ open 2021 · CEBM Level 5
- A Smartphone Intervention to Promote Time Restricted Eating Reduces Body Weight and Blood Pressure in Adults with Overweight and Obesity: A Pilot Study.Nutrients 2021 · CEBM Level 4
- Sex- and age-dependent outcomes of 9-hour time-restricted feeding of a Western high-fat high-sucrose diet in C57BL/6J mice.Cell reports 2021 · CEBM Level 5
- Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19.bioRxiv : the preprint server for biology 2021 · CEBM Level 4
- Temporal Eating Patterns and Eating Windows among Adults with Overweight or Obesity.Nutrients 2021 · CEBM Level 4
- Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome.Cell metabolism 2020 · CEBM Level 4
- Time-Restricted Eating Effects on Body Composition and Metabolic Measures in Humans who are Overweight: A Feasibility Study.Obesity (Silver Spring, Md.) 2020 · CEBM Level 2
- Author Correction: Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption.Nature communications 2020 · CEBM Level 5
- Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study.BMJ open 2020 · CEBM Level 5
- Time-Restricted Eating Alters Food Intake Patterns, as Prospectively Documented by a Smartphone Application.Nutrients 2020 · CEBM Level 2
- Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock.Cell metabolism 2019 · CEBM Level 5
- The arrival of circadian medicine.Nature reviews. Endocrinology 2019 · CEBM Level 5
- Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD.Cell reports 2019 · CEBM Level 5
- Time-Restricted Feeding Improves Glucose Tolerance in Men at Risk for Type 2 Diabetes: A Randomized Crossover Trial.Obesity (Silver Spring, Md.) 2019 · CEBM Level 2
- Time-Restricted Eating to Prevent and Manage Chronic Metabolic Diseases.Annual review of nutrition 2019 · CEBM Level 5
- Timing tweaks exercise.Nature reviews. Endocrinology 2019 · CEBM Level 5
- Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption.Nature communications 2019 · CEBM Level 5
- Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment.Trends in cancer 2019 · CEBM Level 5
- Alternate-Day Fasting Gets a Safe Bill of Health.Cell metabolism 2019 · CEBM Level 5
- Synaptic Specializations of Melanopsin-Retinal Ganglion Cells in Multiple Brain Regions Revealed by Genetic Label for Light and Electron Microscopy.Cell reports 2019 · CEBM Level 5
- Functional diversity of human intrinsically photosensitive retinal ganglion cells.Science (New York, N.Y.) 2019 · CEBM Level 5
- When to Eat: The Importance of Eating Patterns in Health and Disease.Journal of biological rhythms 2019 · CEBM Level 5
- Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.Nature 2018 · CEBM Level 5
- The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding.Cell metabolism 2018 · CEBM Level 5
- Diurnal transcriptome atlas of a primate across major neural and peripheral tissues.Science (New York, N.Y.) 2018 · CEBM Level 5
- Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study.Nutrition and healthy aging 2018 · CEBM Level 4
- Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism.Nature communications 2018 · CEBM Level 5
- Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases.Trends in pharmacological sciences 2018 · CEBM Level 5
- Sustained Melanopsin Photoresponse Is Supported by Specific Roles of β-Arrestin 1 and 2 in Deactivation and Regeneration of Photopigment.Cell reports 2018 · CEBM Level 5
- Sleepmore in Seattle: Later school start times are associated with more sleep and better performance in high school students.Science advances 2018 · CEBM Level 3
- Circadian rhythms, time-restricted feeding, and healthy aging.Ageing research reviews 2017 · CEBM Level 5
- A camera-phone based study reveals erratic eating pattern and disrupted daily eating-fasting cycle among adults in India.PloS one 2017 · CEBM Level 4
- Time-restricted feeding for prevention and treatment of cardiometabolic disorders.The Journal of physiology 2017 · CEBM Level 5
- Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies.NPJ aging and mechanisms of disease 2017 · CEBM Level 5
- Health consequences of electric lighting practices in the modern world: A report on the National Toxicology Program's workshop on shift work at night, artificial light at night, and circadian disruption.The Science of the total environment 2017 · CEBM Level 5
- Circadian physiology of metabolism.Science (New York, N.Y.) 2016 · CEBM Level 5
- Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks.PloS one 2016 · CEBM Level 5