4 No source found (not proven false)
NAD levels decline across human development into adulthood.
"NAD, which goes down across development into adulthood, might be a pro-longevity treatment." (said at 0:33:29)
While cross-sectional studies and narrative reviews frequently investigate the hypothesis that NAD+ levels decrease with age across human tissues, no abstract could be successfully fetched within the search limit to verify the specific claim regarding developmental declines into adulthood versus age-related declines in older adulthood.
Transferring plasma from calorically restricted mice into non-restricted mice isolates factors that reproduce the beneficial effects of caloric restriction.
"Most recently does did another really creative experiment where he did caloric restriction of mice and again that's sort of an accepted, you know, beneficial effect in longevity promoting potentially and takes the plasma from mice, puts it into other mice, and again can isolate factors that mimic this effect." (said at 0:50:25)
A systematic search across PubMed and Europe PMC did not identify published studies demonstrating that transferring plasma from calorically restricted mice into non-restricted mice transfers or isolates circulating factors that reproduce the longevity or physiological benefits of caloric restriction. While heterochronic plasma exchange and exercise-induced plasma transfer experiments (e.g., isolating factors like clusterin or GPLD1) are established in the literature, a specific mouse plasma-transfer model reproducing the benefits of dietary caloric restriction could not be verified in the peer-reviewed scientific literature.
A UK study of over 80,000 subjects found that greater exposure to bright light during the day and darker nights correlates with reduced susceptibility to every measured mental health disorder.
"We know 80,000 plus subjects in this in this UK study, the brighter your days, ideally from sunlight, but the brighter your days and the darker your nights, the less susceptible you are to every single mental health condition." (said at 1:46:46)
No publication directly matching the specific study on day/night light exposure and psychiatric disorder susceptibility in >80,000 subjects was located in PubMed records during the search. While large cohort analyses (such as UK Biobank studies) investigate light exposure patterns in relation to various health and circadian outcomes, the specific paper (such as Burns et al., Nature Mental Health, 2023) could not be retrieved from the indexed database during this search session. Consequently, the claim remains unverified under database retrieval rules, which does not necessarily indicate that the claim is false.
Aging and cognitive decline are associated with an increased prevalence of mouth breathing.
"As people get older and their cognitive function goes, they tend to become mouth breathers." (said at 1:41:48)
No published literature was identified supporting the specific claim that cognitive decline or the loss of cognitive function in aging causes or is directly associated with becoming a mouth breather. While physiological changes during sleep in older age can alter nasal versus oral airflow resistance, empirical evidence directly linking progressive cognitive impairment to an increased prevalence of daytime or nighttime mouth breathing was not located in the searched databases. This does not prove the claim is false, but it remains unverified by the available scientific literature.
Unverified means no publication matching the claim was located; it does not prove the claim false. Spotted an error? See the corrections policy - disputes from the people quoted are prioritized.