HoldsUp

Paul Saladino MD · 2023-08-22 · Paul Saladino (host)

Is hair loss reversible?

27 claims checked against research: 4 overstated 2 needing context 18 supported 3 unverified

4

Overstated

0:12:49Paul Saladino (host)overstatedvery low

Taurine supplementation improves longevity in animal models including worms, mice, and primates.

"Along the same vein, there's evidence that taurine, a nutrient that I've been enamored with recently, which has been studied across multiple species and improves longevity in worm models, in mice, and in primates" (said at 0:12:49)

The claim is overstated regarding primates. A landmark 2023 study by Singh and colleagues demonstrated that taurine supplementation significantly extended median lifespan (longevity) by 10% to 12% in mice and increased lifespan in worms (C. elegans) and yeast. However, in middle-aged rhesus monkeys, the study only assessed healthspan parameters over a 6-month period (finding improvements in bone density, body fat, fasting glucose, liver health, and immune markers); it did not test or demonstrate an increase in primate lifespan or longevity.

0:14:43Paul Saladino (host)overstatedmoderate

Phytic acid found in legumes and whole grains binds to divalent cations including zinc, copper, magnesium, and selenium, inhibiting their absorption.

"they also contain phytates that can bind to the mineral, lowering its absorption. So when I talk about phytates, which is essentially phytic acid in things like oats, people always criticize me and say this isn't a big deal. But they do, and they have been shown repeatedly to prevent the absorption of zinc and other minerals, all of the divalent cations. And in fact, all of these minerals studied in the studies that I'll show you in a moment—zinc, copper, magnesium, selenium—these are all divalent cations, can be bound by phytic acid found in legumes and whole grains, and their absorption can be prevented." (said at 0:14:43)

The speaker claims that phytic acid in legumes and whole grains binds to all divalent cations, specifically zinc, copper, magnesium, and selenium, inhibiting their absorption. While phytic acid (myo-inositol hexakisphosphate) is well-established to chelate polyvalent cations and inhibit the intestinal absorption of zinc, iron, calcium, and magnesium, its interaction with selenium and copper differs from the blanket statement made: 1. **Zinc and Magnesium**: Human and animal literature strongly supports that phytate inhibits zinc and magnesium absorption. For example, a controlled stable-isotope study in humans (PMID 8829129) demonstrated that a high-fibre, high-phytate diet significantly lowered fractional absorption and resulted in negative balances for zinc, copper, and magnesium. Reviews also confirm phytic acid as a major dietary inhibitor of zinc absorption (PMID 10801947). 2. **Copper**: Human studies show that while phytate affects zinc and iron, its effect on copper absorption is far weaker or non-existent in typical human diets. Review evidence specifically notes that phytic acid inhibits the absorption of iron, zinc, calcium, and manganese in adults, but *not* copper (PMID 12949395). 3. **Selenium**: Selenium in foods is predominantly absorbed in organic forms (such as selenomethionine) or inorganic oxyanions (selenite/selenate), not as a free divalent metallic cation bound by phytate. In animal studies, dietary phytate actually increased tissue selenium concentrations and glutathione peroxidase activity, showing a positive relationship with selenium status rather than inhibiting its absorption (PMID 7719737). Because phytic acid inhibits zinc and magnesium absorption but does not inhibit copper or selenium absorption in the same manner, broad assertions sweeping all four minerals together overstate the scientific consensus.

0:24:35Paul Saladino (host)overstatedvery low

Deficiencies in iron, vitamin D, folate, vitamin B12, and selenium are linked to premature hair graying or whitening in childhood or early adulthood, and supplementation can improve it.

"Iron, vitamin D, folate, B12, and selenium are vitamins and minerals that may be involved in hair graying or whitening during childhood or early adulthood. Supplementing these deficiencies can improve premature graying." (said at 0:24:35)

Observational case-control studies in adolescents and young adults have identified associations between premature hair graying (canities) and lower serum levels of certain micronutrients, notably ferritin (iron stores) and vitamin B12, as well as vitamin D and calcium. However, the evidence is observational and cross-sectional. There are no robust randomized controlled trials demonstrating that supplementing these vitamins or minerals effectively reverses or improves premature hair graying, making the therapeutic claim overstated.

0:12:51Paul Saladino (host)overstatedvery low

Deficiencies in taurine or taurine supplementation are linked with hair loss and hair growth.

"Well, taurine supplementation or deficiencies in taurine are linked with hair loss." (said at 0:12:51)

Evidence linking taurine to hair biology comes primarily from in vitro laboratory studies and animal models, alongside multi-ingredient dietary supplement trials. In vitro studies on isolated human hair follicles demonstrate that taurine is taken up by the follicle, enhances survival, and protects against TGF-beta1-induced growth inhibition and fibrosis. Additionally, preclinical animal models of alopecia indicate that topical or targeted taurine formulations can mitigate perifollicular oxidative stress and stimulate regrowth. However, there is no robust clinical evidence demonstrating that dietary taurine deficiency directly causes hair loss in humans or that standalone oral taurine supplementation is an established monotherapy for alopecia.

2

Needs context

0:35:32Paul Saladino (host)needs contextlow

Patients with telogen effluvium without acrodermatitis enteropathica have significantly lower serum zinc levels than healthy individuals, and their hair loss can be restored with zinc supplementation.

"Patients with telogen effluvium without acrodermatitis enteropathica also connected with zinc deficiency exhibit decreased serum levels of zinc compared with healthy individuals. Telogen effluvium can be restored by supplementation with zinc." (said at 0:35:32)

Case-control studies show that patients with telogen effluvium (TE) have statistically significant lower mean serum zinc levels compared with healthy controls. However, the assertion that telogen effluvium can be restored simply through zinc supplementation is an overgeneralization; telogen effluvium is multifactorial (often triggered by stress, illness, endocrine issues, or medication), and zinc supplementation has only demonstrated restorative benefits in the subgroup of patients with proven underlying zinc deficiency. Available clinical evidence is primarily observational.

0:46:29Paul Saladino (host)needs contextlow

Megadoses of resveratrol decrease androgen levels in prostate cancer models.

"resveratrol in mega doses is shown to decrease androgens in prostate cancer models." (said at 0:46:29)

Preclinical prostate cancer models and steroidogenesis studies show that high-dose resveratrol can modulate androgen biology, but the effect is primarily on androgen receptor (AR) expression, signaling pathways, and upstream androgen precursor synthesis rather than circulating androgen levels in vivo. In cell models of steroidogenesis, resveratrol inhibits CYP17A1 activity and reduces androgen synthesis. In prostate cancer cell and rodent models, it downregulates androgen receptor expression and AR-mediated transcription. However, in transgenic prostate cancer animal models and human trials administering high doses of resveratrol, circulating testosterone and dihydrotestosterone (DHT) levels remained unchanged, even while circulating androgen precursors (such as DHEA and DHEAS) were reduced.

18

Supported by research

0:10:45Paul Saladino (host)supportedmoderate

Approximately 90% of human hair is in the anagen phase which can last for years, around 2% is in the catagen phase, and roughly 10% is in the telogen phase.

"Now, 90% of our hair is in the anagen phase and it can last for years. This is hair growth. Only 2% is in this catagen phase, maybe 10%, give or take, is in the telogen phase." (said at 0:10:45)

The speaker's statement reflects the long-established consensus figures for human scalp hair follicle distribution across hair cycle phases: 85%–90% in the anagen (growth) phase—which typically lasts several years—1%–2% in the catagen (regression) phase, and 10%–15% in the telogen (resting) phase. While recent ex vivo microscopic research in specific patient cohorts suggests the catagen fraction may be higher in certain scalp samples, the stated percentages accurately represent the standard physiological baseline.

0:18:51Paul Saladino (host)supportedlow

A cross-sectional study found that all male patients with androgenetic alopecia had deficiencies in zinc, copper, magnesium, selenium, vitamin B12, vitamin E, vitamin D, and folic acid/folate.

"This is a study, "A Cross-sectional Study of Plasma Trace Elements and Vitamin Content in Androgenetic Alopecia in Men." And I will highlight here that they say, it was shown that all patients with androgenetic alopecia (AGA) have a deficiency of elements zinc, copper, magnesium, selenium, vitamins B12, E, D, and folic acid is what they say in the paper." (said at 0:18:51)

The host accurately quoted the findings of a 2021 cross-sectional study examining plasma trace element and vitamin status in men with androgenetic alopecia (AGA). The study evaluated 50 male AGA patients against 25 healthy controls and reported that all patients with AGA presented with deficiencies in zinc, copper, magnesium, selenium, vitamin B12, vitamin E, vitamin D, and folic acid. Because these results originate from a single cross-sectional observational study with a small sample size, the overall certainty of evidence for this finding is low.

0:22:31Paul Saladino (host)supportedlow

In a study of 48 males with androgenetic alopecia treated with 5% topical minoxidil, zinc deficiency was the most common predictor of treatment failure or success.

""Plasma Zinc Levels in Males with Androgenetic Alopecia as Possible Predictors of the Subsequent Conservative Therapy's Effectiveness." What the authors of this paper find was that in 48 patients with different stages of this androgenetic alopecia who were treated with 5% topical minoxidil and these trace elements, that the zinc deficiency was the most common predictor of failure or success of that therapy." (said at 0:22:31)

The host accurately summarizes a 2020 study of 48 males with androgenetic alopecia (PMID 32456296). In this cohort treated with 5% topical minoxidil alongside micronutrient corrections, the researchers assessed genetic, hormonal, metabolic, vitamin, and mineral parameters. Zinc was the only examined nutrient or biomarker that significantly differed between treatment responders and non-responders, showing an overall predictive accuracy of 72.3% for therapeutic success. The evidence is graded low certainty due to the small sample size and observational design.

0:25:37Paul Saladino (host)supportedvery low

L-carnitine supplementation has been shown to promote human hair growth in vitro.

"So when I came across studies like this one, "L-Carnitine Promotes Hair Growth In Vitro," I find it to be interesting, and I think that it's probably pretty valid." (said at 0:25:37)

A 2007 in vitro study by Foitzik et al. directly demonstrated that L-carnitine-L-tartrate stimulated hair shaft elongation in cultured human hair follicles compared to vehicle-treated controls, while also prolonging the anagen growth phase, upregulating proliferation, and reducing apoptosis in follicular keratinocytes.

0:13:21Paul Saladino (host)supportedlow

Deficiencies of the amino acid L-lysine are linked with hair loss.

"and also deficiencies of the amino acid L-lysine have been linked with hair loss." (said at 0:13:21)

Published dermatological and nutritional literature links inadequate levels or suboptimal intake of the essential amino acid L-lysine to hair loss, particularly chronic telogen effluvium (persistent hair shedding) in women, often interacting with iron and ferritin status. However, the evidence base is limited, deriving primarily from small clinical and open-label/double-blind studies assessing combined L-lysine and iron supplementation.

0:20:00Paul Saladino (host)supportedhigh

One pound of meat contains approximately 100 milligrams of magnesium.

"about one pound of meat has around 100 milligrams of magnesium." (said at 0:20:00)

The claim that one pound (approximately 454 g) of meat contains around 100 mg of magnesium is supported by nutritional data and published muscle tissue analysis. Raw beef muscle typically contains approximately 20–25 mg of magnesium per 100 grams (corresponding to roughly 90–115 mg per pound), and thermal processing such as grilling, roasting, or frying concentrates mineral content further per unit weight. For instance, evaluation of bovine longissimus muscle cuts demonstrates magnesium concentrations within this expected range across various breeds and cuts (PMID: 25828160, PMID: 24526320).

0:20:38Paul Saladino (host)supportedmoderate

Brazil nuts contain selenium in the form of selenomethionine, whereas animal foods provide selenium in the form of selenocysteine.

"Selenomethionine is the form found in Brazil nuts, and selenocysteine is the form found in animal foods." (said at 0:20:38)

Nutritional biochemistry and selenium speciation research confirm that plant sources such as Brazil nuts (Bertholletia excelsa) synthesize and accumulate selenium predominantly as organic selenomethionine (and related derivatives), whereas animal tissues and foods provide selenium primarily in the form of selenocysteine incorporated into functional selenoproteins (with smaller amounts of selenomethionine non-specifically incorporated from animal feed).

0:30:15Paul Saladino (host)supportedmoderate

An oral supplement containing hydrolyzed fish collagen, taurine, cysteine, methionine, iron, and selenium improves the clinical efficacy of anti-hair loss treatments in subjects with AGA, FAGA, or chronic telogen effluvium.

"An oral supplement containing hydrolyzed fish collagen, taurine, cysteine, methionine, iron, and selenium has demonstrated to improve the clinical efficacy of specific anti-hair loss treatments in subjects with AGA, FAGA, or chronic telogen effluvium." (said at 0:30:15)

The claim directly reflects the findings and conclusion of a prospective, randomized, assessor-blinded controlled trial (n = 83) evaluating an oral supplement containing hydrolyzed fish-origin collagen, taurine, cysteine, methionine, iron, and selenium. In the trial, subjects with androgenetic alopecia (AGA/FAGA) or chronic telogen effluvium (TE) received either standard hair loss drug therapy alone or standard drug therapy plus the oral supplement for 12 weeks. The combination group achieved significantly higher global assessment scores (GAS) based on blinded photographic evaluation at 12 weeks compared to drug therapy alone (1.67 ± 0.16 vs. 0.66 ± 0.20, p < 0.001).

0:31:16Paul Saladino (host)supportedhigh

Taurine is found exclusively in animal foods.

"taurine is one of my favorite nutrients and supplements these days, again only occurring in animal foods" (said at 0:31:16)

Dietary taurine is found almost exclusively in animal-source foods such as meat, poultry, seafood, and dairy products, and is virtually absent from plant foods. Comprehensive nutrient and amino acid composition profiling of plant- and animal-derived foodstuffs confirms that plants lack taurine.

0:31:46Paul Saladino (host)supportedvery low

In vitro studies show that taurine is taken up by human hair follicles, promotes hair survival, and prevents TGF-beta 1-induced inhibitory effects on hair growth.

"We showed that taurine was taken up by the connective tissue sheath, proximal outer root sheath, and hair bulb, promoted hair survival in vitro, and prevented TGF-beta 1-induced deleterious effects on the hair follicle." (said at 0:31:46)

A 2006 in vitro study evaluated isolated human hair follicles maintained in culture and demonstrated that taurine is actively taken up by the connective tissue sheath, proximal outer root sheath, and hair bulb. The study confirmed that taurine improved in vitro hair follicle survival and counteracted the inhibitory and deleterious effects induced by transforming growth factor-beta 1 (TGF-beta 1). Because this evidence comes exclusively from isolated organ culture/in vitro models, clinical certainty regarding in vivo hair growth in humans remains very low.

0:32:48Paul Saladino (host)supportedvery low

Clinical guidance for managing female hair loss indicates optimal hair growth parameters require serum B12 between 300 and 1,000 ng/L, hemoglobin above 13 g/dL, and serum ferritin above 70 ng/mL.

"in this article titled "Management of Hair Loss in Women," you want the B12 level to be between 300 and 1,000 nanograms per liter... Hemoglobin levels greater than 13 grams per deciliter. Serum ferritin concentrations greater than 70 nanograms per milliliter or greater." (said at 0:32:48)

The statement accurately quotes the published review article "Management of hair loss in women" (Rushton, 1993), which proposes that optimal hair growth potential requires serum vitamin B12 levels between 300 and 1,000 ng/L, hemoglobin concentrations above 13.0 g/dL, and serum ferritin of at least 70 ng/mL. However, these specific target ranges originate from narrative clinical guidance and expert review rather than robust randomized clinical trials.

  • supports: Management of hair loss in women. (Dermatologic clinics 1993) · cited 39x in the literature
    "An optimal hair growth potential is considered to exist when specific parameters for biochemical variables are operating. These include red blood cell and serum folate concentrations within the normal range, serum vitamin B12 levels between 300 and 1000 ng/L, hemoglobin levels greater than 13.0 g/dL, and serum ferritin concentrations of 70 ng/mL or greater." (abstract, passage verified)
    pubmed
0:34:21Paul Saladino (host)supportedvery low

Zinc supplementation serves as an effective adjuvant therapy for alopecia areata in patients who have low serum zinc levels.

"The title of the study is "The Therapeutic Effect and the Changed Serum Zinc Level after Zinc Supplementation in Alopecia Areata Patients"... The conclusion is that "Zinc supplementation needs to be given to alopecia areata patients who have a low serum zinc level. We suggest zinc supplementation could be an adjuvant therapy for alopecia areata patients who have a low serum zinc level" (said at 0:34:21)

The speaker accurately cites the title and conclusions of a 2009 study published in Annals of Dermatology (Park et al., PMID 20523772). In this uncontrolled study of 15 alopecia areata patients with low serum zinc levels receiving oral zinc gluconate for 12 weeks, serum zinc levels significantly increased and hair regrowth was observed in 9 of 15 patients (66.7%), though the authors noted this response rate was not statistically significant. Due to the very small sample size (n=15) and lack of a control group, the certainty of evidence for zinc supplementation as an effective adjuvant therapy is very low.

0:44:06Paul Saladino (host)supportedlow

Dietary fat restriction combined with flaxseed supplementation lowers androgens in men with prostate cancer before surgery.

""Pilot Study of Dietary Fat Restriction and Flaxseed Supplementation in Men with Prostate Cancer Before Surgery," etc., etc. That's the title of the study. Basically, you can read the results, but it lowered androgens, guys." (said at 0:44:06)

The speaker accurately cited the title and main hormonal findings of a 2001 pilot trial by Demark-Wahnefried et al. In 25 men with prostate cancer awaiting surgery who followed a low-fat diet supplemented with 30 g/day of flaxseed for an average of 34 days, there were statistically significant decreases in total testosterone and the free androgen index. The certainty is low due to the small sample size and single-arm, pre-post design for circulating hormone levels.

0:44:36Paul Saladino (host)supportedmoderate

Isoflavone-rich soy protein isolate suppresses androgen receptor expression without altering estrogen receptor-beta expression or serum hormone profiles in men at high risk of prostate cancer.

""Isoflavone-Rich Soy Protein Isolate Suppresses Androgen Receptor Expression without Altering Estrogen Receptor-Beta Expression or Serum Hormonal Profiles in Men at High Risk of Prostate Cancer."" (said at 0:44:36)

The statement directly reflects the title and findings of a randomized controlled trial published in The Journal of Nutrition (PMID 17585029). In 58 men at high risk for advanced prostate cancer, daily consumption of 40 g/d isoflavone-rich soy protein isolate (SPI+, providing 107 mg/d isoflavones) for 6 months significantly suppressed androgen receptor (AR) expression in prostate tissue without altering estrogen receptor-beta expression or circulating hormone concentrations.

0:45:07Paul Saladino (host)supportedvery low

Curcumin decreases testosterone production in prostate cancer models via modulation of AKR1C2.

""Modulation of AKR1C2 by Curcumin Decreases Testosterone Production in Prostate Cancer."" (said at 0:45:07)

The statement accurately reflects the findings of a 2018 preclinical study published in Cancer Science (titled 'Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer'). In both human prostate cancer cell lines (LNCaP and 22Rv1) and a transgenic mouse model of prostate cancer (TRAMP), curcumin treatment increased the expression of Aldo-Keto reductase 1C2 (AKR1C2) and decreased intratumoral testosterone and dihydrotestosterone levels. Because the evidence is derived exclusively from in vitro and animal models, certainty for human application remains very low.

0:47:40Paul Saladino (host)supportedlow

Drinking raw milk is associated with decreased rates of asthma, eczema, and allergies compared to drinking pasteurized milk.

"whey protein appears to be helpful for humans from an allergenic perspective, decreasing rates of asthma, eczema, and allergies when people are drinking raw milk versus pasteurized milk." (said at 0:47:40)

Epidemiological studies of farming populations (such as the PARSIFAL and GABRIELA cohorts) have consistently observed an inverse association between the consumption of unprocessed farm milk and the incidence of childhood asthma, allergic rhinitis, and atopic sensitization compared to commercially processed milk. Mechanistic research suggests that heat-sensitive bovine milk proteins (including native whey proteins such as beta-lactoglobulin and lactoferrin) and other bioactive components may modulate immune development and promote anti-inflammatory regulatory T-cell responses. However, certainty is low because evidence is largely observational, and consuming raw cow's milk carries substantial microbiological safety risks from pathogenic bacteria.

0:41:03Paul Saladino (host)supportedlow

The medical literature on post-finasteride syndrome identifies symptoms including loss of libido, erectile dysfunction, decreased ejaculatory volume, penile shrinkage, Peyronie's disease, testicular reduction, gynecomastia, muscle atrophy, and depression.

"Symptoms of PFS, post-finasteride syndrome, include: decrease or complete loss of libido—well, we just stop right there, I don't know if life is worth living without that; low or no reaction to sexual stimulation—gets worse; erectile dysfunction; loss of pleasure or absence of sensation in orgasm; loss of genital sensitivity; decreasing ejaculatory volume; poor semen quality and infertility; penis shrinkage and abnormal penis curvature, which is known as Peyronie's disease; testicular pain; testicular reduction; gynecomastia, which is man boobs; chronic fatigue; muscle weakness; muscle atrophy and/or pain; muscle spasms; joint pain; dry skin; memory problems; slow thinking; comprehension difficulty; depression; suicidal thoughts; anxiety disorders; panic attacks; emotional detachment; and insomnia." (said at 0:41:03)

The host's statement accurately reflects the symptoms documented in the medical literature examining post-finasteride syndrome (PFS). Reviews and survey studies evaluating PFS describe a constellation of persistent sexual, physical, cognitive, and neuropsychiatric symptoms after finasteride cessation. Specifically, literature reviews and clinical surveys document sexual side effects (loss of libido, erectile dysfunction, decreased ejaculatory volume, penile shrinkage, Peyronie's disease/penile curvature, testicular pain and reduction), physical side effects (gynecomastia, muscle weakness, atrophy, and pain, fatigue, dry skin, joint pain), and neurological/psychological symptoms (cognitive impairment, depression, anxiety, panic attacks, suicidal ideation, and insomnia). Because PFS research relies largely on observational data, self-reported patient surveys, and case series, the certainty of the overall body of evidence regarding the causal nature and exact prevalence of these symptoms is low.

0:45:38Paul Saladino (host)supportedmoderate

Studies show that turmeric/curcumin can reduce pain in patients with osteoarthritis.

"there are some studies suggesting that turmeric may benefit people with osteoarthritis pain." (said at 0:45:38)

Multiple systematic reviews and meta-analyses of randomized controlled trials (RCTs) confirm that turmeric and curcumin extracts provide statistically significant reductions in osteoarthritis pain (measured by visual analog scale and WOMAC pain scores) and improve physical function compared to placebo. The pain-relieving effects are often comparable to non-steroidal anti-inflammatory drugs (NSAIDs) with a lower incidence of adverse events, though study heterogeneity and short follow-up durations warrant moderate certainty.

3

No source found (not proven false)

0:15:21Paul Saladino (host)unverifiedvery low

When oysters are eaten together with beans or tortillas, blood zinc absorption is abrogated and reduced to essentially zero.

"It's a study with oysters from, I believe, the 1950s or 1960s showing that if you give people oysters, you'll see the blood levels of zinc rise... And when you give people that oyster with beans or with a tortilla, that absorption of zinc is significantly lessened. The levels of zinc in the blood are abrogated. In fact, they go to essentially zero if beans and tortillas are given together." (said at 0:15:21)

No published record matching the specific claim that consuming oysters alongside beans or tortillas abrogates and reduces plasma zinc absorption to essentially zero was located with retrievable abstract text; this does not prove the claim false.

0:28:36Paul Saladino (host)unverifiedvery low

A supplement formulation called TRX2 containing L-carnitine, zinc, niacin, biotin, BCAAs, and selenium slowed androgenetic alopecia progression and increased the anagen-to-telogen hair ratio both systemically and topically.

"Another study looks at "The Effect of a Food Supplement and a Hair Lotion on the Progression of Androgenetic Alopecia." Note that they did not use a steak lotion. They used a supplement called TRX2, which contained L-carnitine, zinc, niacin, biotin, branched-chain amino acids, and selenium... and in both cases, it did improve the progression of androgenetic alopecia and in some cases led to hair regrowth... both resulted in reduced hair loss rate as well as an increased anagen-to-telogen hair ratio." (said at 0:28:36)

No published record matching a study titled "The Effect of a Food Supplement and a Hair Lotion on the Progression of Androgenetic Alopecia" or evaluating the TRX2 formulation (containing L-carnitine, zinc, niacin, biotin, branched-chain amino acids, and selenium) for androgenetic alopecia progression and anagen-to-telogen ratio was located; this does not prove the claim false.

0:44:46Paul Saladino (host)unverifiedvery low

Consumption of meat and saturated fat can improve androgen receptor density.

"Something that's not been talked about much is androgen receptor density, but one of the things we know is that meat, saturated fat, can improve androgen receptor density." (said at 0:44:46)

No published record matching the claim that consumption of meat and saturated fat improves androgen receptor density was located; this does not prove the claim false. While several studies have examined the influence of exercise, pharmaceutical agents, or total dietary composition on testosterone levels and androgen receptor expression, no peer-reviewed human or animal studies demonstrate that consuming meat or saturated fat increases androgen receptor density.

Unverified means no publication matching the claim was located; it does not prove the claim false. Spotted an error? See the corrections policy - disputes from the people quoted are prioritized.