FoundMyFitness · 2024-08-27 · Rhonda Patrick (host), Layne Norton

Dr. Layne Norton on Building Muscle – Insights on Diet, Training, and Supplements

116 research-tied claims examined: 5 contradicted 13 overstated 14 context 72 supported 12 unverified

12

No source found (not proven false)

0:00:15Layne Nortonunverifiedvery low

In the last few decades, added oils have been one of the biggest sources of increased energy intake in the American diet.

"in the last few decades, added oils are one of the biggest sources of increased energy in the American diet." (said at 0:00:15)

No published record matching the claim that added oils have been one of the biggest sources of increased energy intake in the American diet over the last few decades was located; this does not prove the claim false.

0:29:49Layne Nortonunverifiedvery low

A resistance training study in frail elderly individuals conducted at the University of Illinois demonstrated significant increases in lean mass, muscle cross-sectional area, and MRI-measured muscle quality following 12 to 16 weeks of progressive chair-stand exercises.

"at University of Illinois, where I did my PhD in the exercise phys department, they were doing a study in frail elderly, but basically we're talking about people who had trouble kind of standing up, you know? And they started—their progressive overload was they started them sitting down to a high chair and doing reps with that. After, I think it was 12 or 16 weeks, I can't recall the specific details of the study, they saw significant increases in lean mass, cross-sectional area, muscle quality as imaged by an MRI." (said at 0:29:49)

No published record matching the claimed University of Illinois study in frail elderly individuals demonstrating significant increases in lean mass, muscle cross-sectional area, and MRI-measured muscle quality following progressive chair-stand exercises was located; this does not prove the claim false.

0:33:46Layne Nortonunverifiedvery low

Performing high repetitions with light weights recruits larger muscle fibers as sets approach muscular fatigue.

"And so if you do high reps with low weight, you'll still eventually recruit those larger muscle fibers as you get close to fatigue." (said at 0:33:46)

No published record matching the claim that performing high repetitions with light weights recruits larger muscle fibers as sets approach muscular fatigue was located; this does not prove the claim false.

0:36:14Layne Nortonunverifiedvery low

A meta-regression by James Krieger found that performing 27 to 45 hard sets per week for the triceps produced greater hypertrophy than performing 15 to 25 sets per week.

"There was a regression by James Krieger that even up to like 27 to 45 hard sets per week on triceps produced more muscle growth than I think like 15 to 25 sets per week, something like that." (said at 0:36:14)

No published record matching a meta-regression by James Krieger showing that 27 to 45 sets per week on triceps produced more muscle growth than 15 to 25 sets per week was located; this does not prove the claim false. Published peer-reviewed meta-analyses by Krieger and colleagues on resistance training volume have evaluated weekly volume categories (e.g., <5, 5–9, and 10+ sets per week) without published peer-reviewed triceps-specific meta-regressions contrasting 15–25 versus 27–45 weekly sets.

0:49:00Layne Nortonunverifiedvery low

Full range of motion squats produce greater muscular hypertrophy than partial range of motion half squats.

"so doing full range of motion versus a half squat, right, you get more hypertrophy doing the full squat. There's quite a few studies on this." (said at 0:49:00)

No published record matching the claim that full range of motion squats produce greater muscular hypertrophy than partial range of motion half squats was located; this does not prove the claim false.

1:03:30Layne Nortonunverifiedvery low

Lya Bavoil, French national champion, squatted 496 lb at 150 lb body weight drug-free.

"One of my friends is probably the best female squatter in the world drug-free. She squatted 496 lb at 150 lb body weight. Her name's Lya Bavoil. She's the French national champion, but her knees cave when she squats" (said at 1:03:30)

No published record matching the claim that French powerlifter Lya Bavoil squatted 496 lb at 150 lb body weight drug-free was located in the biomedical literature; this does not prove the claim false, as individual athletic performances and powerlifting federation competition records are typically maintained in sports federation databases rather than peer-reviewed scientific journals.

1:12:55Layne Nortonunverifiedvery low

Soft tissue injuries typically heal within 6 to 12 months.

"Like, yes, tissue injuries tend to cause pain, but soft tissue injuries heal within 6 to 12 months. If you're still having pain after that, it's because your brain has actually made a connection." (said at 1:12:55)

No published record matching the claim that soft tissue injuries typically heal within 6 to 12 months was located; this does not prove the claim false.

1:28:54Layne Nortonunverifiedlow

Elderly individuals, such as 70-year-olds who have never lifted weights, gain a similar amount of muscle as a percentage of starting lean mass when they begin resistance training.

"And so in elderly, we see that too as a percentage. Now, if you take somebody who's 70 years old and never lifted weights before, they're going to not have very much lean mass. But if they start, they'll still gain a similar amount as a percentage of their starting lean mass." (said at 1:28:54)

No published record matching the specific claim that elderly individuals who begin resistance training gain a similar percentage of starting lean mass compared to younger populations was located; this does not prove the claim false.

1:35:46Rhonda Patrick (host)unverifiedvery low

NHANES data shows younger adults consume on average about 1.5 grams of protein per kilogram of body weight per day, while older adults consume about 1.2 grams per kilogram.

"if you look at the NHANES studies and people on average, well, depending on their age, but like younger adults, let's say people that are like 40 and younger, they're getting on average about 1.5 grams per kilogram body weight right now. Older adults more like 1.2, but that's their average consumption." (said at 1:35:46)

No published record matching the specific claim that NHANES data shows younger adults consume an average of approximately 1.5 g/kg/day of protein while older adults consume approximately 1.2 g/kg/day was located; this does not prove the claim false.

2:09:52Rhonda Patrick (host)unverifiedvery low

Individuals with loss-of-function variants or lower levels of PCSK9 have naturally lower lifetime LDL levels and lower cardiovascular and all-cause mortality.

"those studies that you were just talking about, to me, are the argument against that because they're showing people with like natural PCSK9, like when they're having a lower level of it and they have naturally just lower levels of LDL throughout their life, they have a low all-cause mortality, they have a lower cardiovascular-related mortality." (said at 2:09:52)

No published record matching the claim that individuals with loss-of-function variants or lower levels of PCSK9 have naturally lower lifetime LDL levels and lower cardiovascular and all-cause mortality was located; this does not prove the claim false.

2:33:25Layne Nortonunverifiedvery low

Approximately 80% of studies evaluating aspartame show no effect on cancer risk.

"80% of the studies on aspartame show no effect on cancer. Like, I think something like 11% are like a possibly, and 9% are a yes, talking about animal studies." (said at 2:33:25)

No published record matching the claim that approximately 80% of animal studies evaluating aspartame show no effect on cancer risk (with 11% showing possible effect and 9% showing a positive effect) was located; this does not prove the claim false. Published systematic reviews evaluating the toxicological and animal bioassay evidence for aspartame (such as PMID 36493943 and PMID 17828671) assess the evidence qualitatively rather than reporting this specific numerical breakdown, concluding that standard guideline animal bioassays demonstrate a overall lack of carcinogenic potential, while a small minority of non-standard studies (primarily from the Ramazzini Institute) report positive findings that authoritative bodies consider flawed.

48:35:53Layne Nortonunverifiedvery low

Cellular autophagy is elevated in certain cancers and muscle-wasting diseases.

"I mean, autophagy is elevated in some cancers, it's elevated in some wasting diseases. I mean, we were talking about lysosomal protein degradation essentially." (said at 48:35:53)

No published record matching the claim that cellular autophagy is elevated in certain cancers and muscle-wasting diseases was located; this does not prove the claim false.

Unverified means no publication matching the claim was located; it does not prove the claim false. Spotted an error? See the corrections policy - disputes from the people quoted are prioritized.