David Roberts

Phenethyl isothiocyanate (PEITC) from watercress acts synergistically with sulforaphane to stimulate NRF2 five times more than sulforaphane alone.

"And then we add one from watercress. It's called PEITC, phenethyl isothiocyanate. Name's not important, but what is important is that um and this is in the literature and we've shown it in our own tests, it stimulates NRF2 synergistically with sulforaphane. So, 1 + 1 = 5. So, it turns on NRF2 five times more than sulforaphane alone." (said at 0:14:20)

No published record matching the claim that phenethyl isothiocyanate (PEITC) acts synergistically with sulforaphane to stimulate NRF2 five times more than sulforaphane alone was located; this does not prove the claim false. While both sulforaphane and PEITC are well-documented in vitro and ex vivo activators of Nrf2 and downstream phase II antioxidant enzymes, published studies demonstrating a specific 5-fold synergistic co-activation of Nrf2 by this combination were not identified in the peer-reviewed literature.

• context: Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidati… (Pharmacological research 2013) · cited 65x in the literature

  "Mechanistic cell culture studies revealed SFN and PEITC to increase Nrf2 activity and Nrf2-dependent gene expression (γGCS, HO-1, NQO1); this was paralleled in human full skin mRNA." (abstract, results, passage verified)

  pubmedfull study (doi)

Glyphosate causes leaky gut by opening intestinal epithelial tight junctions.

"glyphosate's known to cause leaky gut opening the tight junctions. And so, he did this cell culture study opening with opening tight junctions with glyphosate, but then giving you know broccoli sulforaphane and showing that it's protective against that." (said at 0:28:54)

No published record matching the claim that glyphosate opens intestinal epithelial tight junctions to cause leaky gut and that broccoli-derived sulforaphane protects against glyphosate-induced tight junction disruption in cell culture was located; this does not prove the claim false.

Sulforaphane protects intestinal epithelial tight junctions from damage caused by glyphosate.

"And so, he did this cell culture study opening with opening tight junctions with glyphosate, but then giving you know broccoli sulforaphane and showing that it's protective against that." (said at 0:28:54)

No published record matching a cell culture study showing that sulforaphane protects intestinal tight junctions specifically against glyphosate-induced disruption was located; this does not prove the claim false. While sulforaphane has been investigated in in vitro models for protecting intestinal epithelial integrity against various inflammatory and oxidative stressors (such as TNF-α), direct published evidence testing sulforaphane against glyphosate in tight-junction assays has not been identified in the peer-reviewed biomedical literature.

A 10 mg dose of sulforaphane reduces interleukin-6 (IL-6) levels by 30% within 24 hours.

"two capsules so 10 mg of sulforaphane um decreases IL-6 so uh so an inflammatory marker 30% in 24 hours." (said at 0:39:41)

No published record matching the claim that a 10 mg dose of sulforaphane decreases interleukin-6 (IL-6) levels by 30% within 24 hours was located; this does not prove the claim false. While sulforaphane has been investigated for its antioxidant and anti-inflammatory properties in preclinical models and small human trials, clinical data demonstrating this specific acute percentage reduction at a 10 mg dose in humans are lacking.

People inhale more microplastics from breathing than they ingest from food and drink.

"you actually get more microplastics from breathing than what you do ingestion." (said at 1:02:22)

No published record matching the claim that people inhale more microplastics from breathing than they ingest from food and drink was located; this does not prove the claim false.