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Morgan Levine

Altos Labs / Yale University School of Medicine

Morgan Levine, PhD, is an assistant professor of pathology at the Yale University School of Medicine and a Founding Principal Investigator at Altos Labs. Her research centers on the science of biological aging, epigenetics, and the development of aging metrics such as the PhenoAge clock. Her published work investigates epigenetic age acceleration, blood methylation tests across physiological systems, mitochondrial function, and the effects of lifestyle interventions on biological age.

37 claims checked on air: 1 contradicted 1 overstated 32 supported 3 unverified

What they said on air - unverified

6 citing their own research

0:24:05unverifiedvery lowMorgan Levine, PhD, on PhenoAge and the Epigenetics of Age A

Epigenetic clock methylation changes occur most rapidly during development, become steady around age 20, and slow down after age 80.

"The epigenetic clocks show a totally different pattern: it's still not linear, but actually most of the changes happen during development. So you have this huge increase in epigenetic age between—we can even measure it in fetal samples—and then it kind of starts becoming more linear and steady around age 20. And then interestingly, it actually slows down again in very late life, so after let's say age 80." (said at 0:24:05)

No published record matching the claim that epigenetic clock methylation changes occur most rapidly during development, stabilize around age 20, and slow down after age 80 was located; this does not prove the claim false.

0:25:30unverifiedvery lowMorgan Levine, PhD, on PhenoAge and the Epigenetics of Age A

Developing a chronic disease is associated with a shortened time interval to developing subsequent chronic diseases.

"And we do know, not looking at epigenetics, that once you get a disease, it's actually shorter time to each subsequent disease." (said at 0:25:30)

No published record matching the claim that developing a chronic disease is associated with a shortened time interval to each subsequent disease was located; this does not prove the claim false.

1:14:08unverifiedvery lowMorgan Levine, PhD, on PhenoAge and the Epigenetics of Age A

Exercise has been shown to reverse diabetes better than metformin.

"Or they've even shown you can reverse diabetes through exercise or any of these things better than metformin." (said at 1:14:08)

No published record matching the claim that exercise reverses diabetes better than metformin was located; this does not prove the claim false. While landmark clinical trials such as the Diabetes Prevention Program demonstrated that intensive lifestyle interventions (combining diet and physical activity) were more effective than metformin at preventing or delaying the onset of type 2 diabetes in individuals with prediabetes, these findings pertain to diabetes prevention rather than the reversal or remission of established type 2 diabetes.

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