Simone Collins
Simone Collins is an author and pronatalist advocate. Her work focuses on global fertility rates and demographic decline.
7 claims checked on air: 2 context 1 overstated 2 supported 2 unverified
What they said on air
In a few years, US Social Security beneficiaries will receive under 80% of their expected payments.
"boomers who are like like not my problem, they're still in just a few years going to be receiving only like under 80% of their expected social security payments, which are being paid for by Gen Z who's not expecting anything." (said at 0:01:32)
No published record matching the claim regarding Social Security benefit reductions to under 80% upon trust fund depletion was located in the fetched database records; this does not prove the claim false.
Women in developed countries with low social support experience a short-term hit to happiness during early childhood before it rises in the long run.
"Women especially do take a short-term hit per the research that I've seen, and then it goes up over the long run." (said at 1:03:42)
Longitudinal demographic research confirms the 'parenthood happiness paradox': parents—particularly mothers—often experience an initial drop in subjective well-being and life satisfaction during the early transition to parenthood and early childhood years, particularly in institutional contexts lacking strong family policy supports, whereas long-term parental well-being tends to recover or exceed that of non-parents in later life stages.
- supports: Parental Well-being Surrounding First Birth as a Determinant of Further Parity Progression… (Demography 2015) · cited 96x in the literature
"Analyzing longitudinal data from Germany, we find that the experience during the transition to parenthood, as measured by changes in subjective well-being, predicts further parity progression. A drop in well-being surrounding first birth predicts a decreased likelihood of having another child." (abstract, results, passage verified)
pubmedfull study (doi) - context: The Parenthood Happiness Puzzle: An Introduction to Special Issue. (European journal of population = Revue europeenne de demographie 2016) · cited 44x in the literature
"Contrary to conventional wisdom, recent studies argue that parenthood is not necessarily related to higher parental subjective well-being (SWB). However, parenthood remains an important aspect of adults' lives, also in highly developed societies where childbearing has become optional, financially expensive and affecting other goals in life." (abstract, background, passage verified)
pubmedfull study (doi)
Severe morning sickness is caused by an identified protein combination, and a treatment targeting it is currently in clinical trials.
"there's actually a cure for morning sickness that's in trials cuz we identified the specific protein combination that causes severe morning sickness." (said at 2:16:15)
Genetic and mechanistic studies have established that severe morning sickness (hyperemesis gravidarum) is primarily driven by fetal production of the hormone/protein GDF15 (growth and differentiation factor 15) acting on maternal brainstem receptors, combined with maternal sensitivity determined partly by prepregnancy exposure. Earlier genome-wide association studies also implicated IGFBP7 alongside GDF15. Describing this discovery as identifying a 'protein combination' is an oversimplification, and asserting that a 'cure' is currently in clinical trials is overstated: while researchers have proposed preventive strategies (such as prepregnancy GDF15 desensitization or metformin) and therapeutic targets (GDF15/GFRAL blockade), these remain in preclinical, observational, or early investigational stages rather than proven cures.
- context: Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum. (Nature communications 2018) · cited 193x in the literature
"Two loci, chr19p13.11 and chr4q12, are genome-wide significant (p < 5 × 10 -8 ) in both association scans and are replicated in an independent cohort. The genes implicated at these two loci are GDF15 and IGFBP7 respectively, both known to be involved in placentation, appetite, and cachexia." (abstract, results, passage verified)
pubmedfull study (doi) - supports: GDF15 linked to maternal risk of nausea and vomiting during pregnancy. (Nature 2024) · cited 199x in the literature
"Our findings support a putative causal role for fetally derived GDF15 in the nausea and vomiting of human pregnancy, with maternal sensitivity, at least partly determined by prepregnancy exposure to the hormone, being a major influence on its severity. They also suggest mechanism-based approaches to the treatment and prevention of HG." (abstract, results, passage verified)
pubmedfull study (doi) - context: Prepregnancy metformin use associated with lower risk of severe nausea and vomiting of pre… (American journal of obstetrics and gynecology 2025) · cited 5x in the literature
"Metformin, which is routinely used before and after conception, may be a safe and affordable treatment to offer patients with a history of hyperemesis gravidarum to decrease the chance of reoccurrence. Clinical trials are warranted to investigate metformin use before pregnancy to lower the risk for hyperemesis gravidarum, thereby mitigating the associated adverse maternal and offspring outcomes." (abstract, conclusions, passage verified)
pubmedfull study (doi)
Qualitative research by Catherine Ruth Pakaluk on college-educated American women with five or more children found that most did not initially plan to have large families, but a positive experience with their first child served as the tipping point.
"Catherine Ruth Pakaluk did a lot of research on studying highly values motivated people who already have four. ... Her what she found when she when she interviewed these women was for so many of them and this is to your point their experience with their first child was really the tipping point. None of them planned on having a lot of kids and what happened that she noticed again and again was these women had such a great experience with their first kid." (said at 3:03:45)
No published record matching the qualitative research findings described by Catherine Ruth Pakaluk was located; this does not prove the claim false.
Being either significantly underweight or significantly overweight reduces a woman's likelihood of getting pregnant.
"Yeah, if you're super underweight or super overweight, you're less likely to get pregnant." (said at 3:30:04)
Large prospective cohort studies and a 2024 meta-analysis confirm that being outside the normal body mass index (BMI) range—both underweight and overweight/obese—is associated with reduced fecundability (the per-cycle probability of conception), prolonged time-to-pregnancy, and increased risk of subfertility or infertility in women.
- supports: Association between preconception body mass index and fertility in adult female: A systema… (Obesity reviews : an official journal of the International Association for the Study of Obesity 2024) · cited 20x in the literature
"Female with overweight/obesity (FOR = 0.85; 95% CI: 0.80, 0.90), obesity (FOR = 0.76; 95% CI: 0.69, 0.83), and overweight (FOR = 0.93; 95% CI: 0.88, 0.99) was associated with the significant time-to-pregnancy (TTP) prolongation (reduced fecundability). Interestingly, underweight was moderately associated with prolonged TTP in females (FOR = 0.95; 95% CI: 0.91, 0.99). Female overweight/obesity was associated with an increased risk of subfecundity (OR = 1.44; 95% CI: 1.20, 1.72) and infertility (OR = 1.60, 95% CI: 1.31-1.94)." (abstract, results, passage verified)
pubmedfull study (doi) - supports: Preconception and Early-Pregnancy Body Mass Index in Women and Men, Time to Pregnancy, and… (JAMA network open 2024) · cited 37x in the literature
"Compared with normal weight in women, underweight (odds ratio [OR], 1.88 [95% CI, 1.22-2.88]), overweight (OR, 1.35 [95% CI, 1.11-1.63]), and obesity (OR, 1.67 [95% CI, 1.30-2.13]) were associated with increased odds of subfertility." (abstract, results, passage verified)
pubmedfull study (doi)
A woman's ability to conceive declines linearly starting from age 20.
"Ability to conceive declines literally linearly for women from age 20?" (said at 3:34:32)
Preconception cohort studies and historical demographic analyses demonstrate that natural fecundability (the per-cycle probability of conception) peaks in the early 20s and decreases progressively with age. Some prospective cohorts (e.g., Wesselink et al., 2017) and historical natural-fertility models (e.g., Wood, 2000) describe an approximately linear decline in per-cycle conception rates from age 20–24 through age 45. However, the term "literally linear" requires context: several studies find that fecundability remains relatively stable or decreases gradually through the late 20s and early 30s, followed by a steeper, accelerated decline in the mid-to-late 30s.
- context: The age pattern of fecundability: an analysis of French Canadian and Hutterite birth histo… (Social biology 2000) · cited 32x in the literature
"2) effective fecundability peaks at age 20 for the Hutterites, and in the early to mid-20s for the French Canadians; 3) Hutterite effective fecundability declines almost linearly from age 20 to 45, and French Canadian effective fecundability declines slowly from its peak to the early 30s, and more rapidly at older ages" (abstract, results, passage verified)
pubmedfull study (doi) - context: Increased infertility with age in men and women. (Obstetrics and gynecology 2004) · cited 521x in the literature
"The percentage infertility was estimated at 8% for women aged 19-26 years, 13-14% for women aged 27-34 years and 18% for women aged 35-39 years." (abstract, results, passage verified)
pubmedfull study (doi) - context: Age and fecundability in a North American preconception cohort study. (American journal of obstetrics and gynecology 2017) · cited 118x in the literature
"In this preconception cohort study of North American pregnancy planners, increasing female age was associated with an approximately linear decline in fecundability." (abstract, conclusions, passage verified)
pubmedfull study (doi)
De novo mutations in male sperm begin rising at age 18.
"Men's mutations in their sperm start rising at age 18?" (said at 3:34:38)
Paternal de novo germline mutations accumulate continuously with paternal age at a rate of approximately 1.5 to 2 mutations per year. However, this accumulation is driven by ongoing spermatogonial stem cell divisions, a process that begins at puberty (typically around age 12 to 14) rather than starting specifically at age 18. Age 18 is commonly used as an early-adulthood reference baseline in demographic and genetic modeling, but biological mutation accumulation begins earlier.
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