HoldsUp

Oliver Amdrup-Chamby

Puori

Oliver Amdrup-Chamby is the co-founder of Puori. He focuses on topics related to health, fitness, protein quality, aging, and dietary supplements. There are no academic publications listed for him in the provided context.

20 claims checked on air: 3 context 8 supported 9 unverified

What they said on air

0:01:00supportedhighThe Protein Mistakes Costing You Muscle in Midlife | Puori

The traditional baseline dietary recommendation for protein intake was 0.8 grams per kilogram of body weight.

"I think the old recommendation we had was like 0.8 grams per kilo, right?" (said at 0:01:00)

The standard Recommended Dietary Allowance (RDA) for protein established by the Institute of Medicine (now the National Academies of Sciences, Engineering, and Medicine) and the World Health Organization is 0.8 g of protein per kilogram of body weight per day for healthy adults. This baseline recommendation was established primarily to prevent deficiency and maintain nitrogen balance.

0:02:18supportedhighThe Protein Mistakes Costing You Muscle in Midlife | Puori

Dietary protein is biochemically composed of 20 different amino acids.

"When you look at what the protein is built up of, it's built up of 20 different amino acids." (said at 0:02:18)

Biochemically, natural dietary and biological proteins are polymers constructed from 20 standard (proteinogenic/canonical) amino acids encoded by the universal genetic code.

0:03:20supportedhighThe Protein Mistakes Costing You Muscle in Midlife | Puori

The Digestible Indispensable Amino Acid Score (DIAAS) is a scoring system used to measure the quality of dietary protein sources.

"And there's there's you know, a score system called the DIAAS score, which is basically um basically measuring quality of each amino acid like each protein source." (said at 0:03:20)

The claim is accurate. The Digestible Indispensable Amino Acid Score (DIAAS) is an established scoring method adopted by FAO/WHO to evaluate the quality of dietary protein sources by determining the true ileal digestibility of individual indispensable amino acids relative to reference scoring patterns.

0:05:50supportedmoderateThe Protein Mistakes Costing You Muscle in Midlife | Puori

Older adults require a higher amount of leucine per serving (around 2.5 grams or more) to trigger muscle protein synthesis due to anabolic resistance.

"if I need to meet that like maybe 2 g of leucine per serving to hit muscle protein synthesis—or it may be even more depending on age." That's something that, you know, as we age you need actually a higher" (said at 0:05:50)

Aging is characterized by anabolic resistance, in which skeletal muscle exhibits a blunted sensitivity to the stimulatory effects of dietary protein and essential amino acids. Evidence demonstrates that the threshold for activating mechanistic target of rapamycin complex 1 (mTORC1) and stimulating muscle protein synthesis (MPS) increases with age, requiring higher per-serving doses of protein and leucine (typically ~2 to 3 grams of leucine, often provided by 20–30+ grams of high-quality protein) to achieve a postprandial MPS response comparable to younger individuals.

0:07:36supportedmoderateThe Protein Mistakes Costing You Muscle in Midlife | Puori

When intake of amino acids is deficient, the body prioritizes distributing amino acids to vital organs before skeletal muscle or hair.

"if you only get a little bit of leucine and a little bit of like like small amount of it, it will start with the organs. Like the the most important part will get that amino acids first. So you will have a much harder time, you know, keeping muscle mass, all the other like hair" (said at 0:07:36)

Basic nutritional physiology and metabolic studies support the concept that under conditions of low or restricted protein/amino acid intake, dietary amino acids are prioritized for first-pass utilization and maintenance in central/vital organs (such as the liver and gastrointestinal tract) before surplus amino acids are made available via systemic circulation to support peripheral tissue synthesis such as skeletal muscle and integumentary structures (e.g., hair). In animal models of protein malnutrition, the partitioning of amino acids preserves visceral organ protein mass and turnover at the expense of skeletal muscle growth and accretion.

0:19:20unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

A Clean Label Project study found that 47% of top-selling protein powders in the United States exceeded California Proposition 65 limits for heavy metals.

"We've seen the Clean Label Project's category study in 2025 come out like saying that 47% of America's best-selling protein—so, they tested 83% of the category. So, it's a very representative like like you know, snapshot of the industry. And out of that, 47% was above Proposition 65 standards for heavy metals." (said at 0:19:20)

No published record matching a Clean Label Project study finding that 47% of top-selling protein powders exceeded California Proposition 65 heavy metal limits was located; this does not prove the claim false.

0:19:40unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

The Clean Label Project's category study tested 83% of America's top-selling protein powder products.

"We've seen the Clean Label Project's category study in 2025 come out like saying that 47% of America's best-selling protein—so, they tested 83% of the category." (said at 0:19:40)

No published peer-reviewed record matching the Clean Label Project's category study findings, methodology, or specific market coverage percentages for protein powder products was located; this does not prove the claim false.

0:19:51unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

Lead was the primary heavy metal found exceeding Proposition 65 standards in the Clean Label Project protein powder study.

"And the main one was lead." (said at 0:19:51)

No published record matching the claim that lead was the primary heavy metal found exceeding California Proposition 65 standards in the Clean Label Project protein powder study was located; this does not prove the claim false.

0:20:12unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

In the Clean Label Project study, 77% of plant-based protein powders tested exceeded Proposition 65 standards for heavy metals.

"when we look at the plant proteins in that study, they were, you know, I think it was 77% of the plant proteins was above Proposition 65 standards on these heavy metals." (said at 0:20:12)

No published peer-reviewed record matching the Clean Label Project study finding that 77% of plant-based protein powders exceeded California Proposition 65 standards for heavy metals was located; this does not prove the claim false.

0:20:34supportedhighThe Protein Mistakes Costing You Muscle in Midlife | Puori

A complete protein is defined as containing all nine essential amino acids.

"having all these nine essential amino acids. That's how you talk about a complete protein versus an incomplete." (said at 0:20:34)

In nutritional science, a complete protein is conventionally defined as a dietary protein source that contains all nine essential amino acids (histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine) in adequate proportions to meet human physiological requirements, in contrast to incomplete proteins that lack or are insufficient in one or more essential amino acids.

0:22:38supportedmoderateThe Protein Mistakes Costing You Muscle in Midlife | Puori

Cacao plants bioaccumulate heavy metals from the soil into cacao beans.

"because if you want to use real organic cacao beans, cacao beans are also really good at accumulating heavy metals out of the soil." (said at 0:22:38)

Agricultural and environmental chemistry studies consistently confirm that the cacao plant (Theobroma cacao L.) readily absorbs and bioaccumulates heavy metals—most notably cadmium—from the soil, translocating and partitioning them into leaves and beans. The degree of accumulation depends on soil characteristics (such as pH and cadmium bioavailability), geographic factors, and genetic cultivars of the plant.

0:26:03unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

California Senate Bill 1033 was introduced to require third-party validated testing for heavy metals in protein powders and protein-added products.

"California for the first time actually looking into creating a new bill. So, the SB 1033, which is like for us like like almost a dream come true because it will give the industry guardrails and there will be set of standard that you have to apply to. Meaning and this is just heavy metals for now, which is, you know, four to is the is the biggest issue in the protein category for sure. But that means that when these come out and hopefully this bill will pass, California will set standards that you cannot sell protein powder or protein added products without having a third-party test that is validated." (said at 0:26:03)

No published record matching the claim that California Senate Bill 1033 was introduced to require third-party validated testing for heavy metals in protein powders and protein-added products was located; this does not prove the claim false.

0:31:56needs contextmoderateThe Protein Mistakes Costing You Muscle in Midlife | Puori

Whey protein concentrate retains healthy fats, immunoglobulins, and immune-supporting bioactive compounds that are filtered out in whey protein isolate.

"We have chosen to use the concentrate because it's actually much closer to the real whole food. So, we haven't, you know, pulled out all the different, you know, healthy fats, all the immunoglobulins, and all the different, you know, immune-supporting benefits that are actually is in a high-quality whey." (said at 0:31:56)

Dairy processing and compositional analyses confirm that whey protein concentrate (WPC) and whey protein isolate (WPI) differ primarily due to extensive filtration and purification processes (such as microfiltration, ultrafiltration, and ion-exchange chromatography). WPC typically contains 34–80% protein and retains higher proportions of native non-protein components from milk, including residual milk lipids/fats, phospholipids, and various bioactive glycoforms and minor proteins. In contrast, WPI is further processed to achieve ≥90% protein purity, which selectively removes almost all fats and lactose, and can alter or diminish certain bioactive fractions and glycoprotein structures depending on the isolation method used. However, describing WPC as retaining unique immune benefits that are completely lost in WPI requires qualification: WPI still retains major bioactive intact whey proteins (such as beta-lactoglobulin, alpha-lactalbumin, and lactoferrin), though the lipid and certain glycan/immunoglobulin profiles are substantially reduced.

0:32:13unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

Whey protein isolate processing removes the lactose present in whey concentrate.

"And and I would also say if you if you're lactose intolerant, the isolate that you know, gets the out of there." (said at 0:32:13)

No published record matching the specific claim that whey protein isolate processing removes the lactose present in whey concentrate to make it suitable for individuals with lactose intolerance was located; this does not prove the claim false.

0:33:48needs contextlowThe Protein Mistakes Costing You Muscle in Midlife | Puori

Testing studies show whey protein powder has 5 to 10 times lower heavy metal levels than plant-based protein powders, while beef protein has approximately half the heavy metal content of plant protein.

"So the main in these studies, I think the the cleanest overall was whey. So if you look at heavy metals. Uh then second cleanest was the beef-based. But they were only like um So I think it was like five or 10 times cleaner whey-based versus plant in general. Um and beef was like twice as clean as plant in general." (said at 0:33:48)

Independent and commercial testing analyses (such as reports by the Clean Label Project and Consumer Reports) have found that plant-based protein powders generally contain higher average concentrations of heavy metals (such as lead, arsenic, and cadmium) compared to animal-derived powders like whey, primarily because plants absorb minerals and metals directly from agricultural soil. Analyses assessing these datasets confirm that whey protein supplements exhibit the lowest heavy metal contamination and calculated hazard indices. However, specific multipliers (such as whey having 5 to 10 times lower levels or beef having half the levels of plant proteins) reflect variable snapshot testing of commercial brands rather than fixed biological ratios. Furthermore, toxicological risk assessments of these reported levels indicate that typical consumption of protein powders across types remains below adverse health risk thresholds (Hazard Index < 1).

0:34:16unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

Consumer Reports testing showed heavy metal contamination across protein powder crop types was not flavor-dependent.

"and I think that was in Consumer Reports, they did another study on protein powder as well, that they actually said it was they couldn't see that it was flavor dependent where the heavy metals. They would see it in both the in both type of crops as well." (said at 0:34:16)

No published record matching the claim that Consumer Reports testing showed heavy metal contamination in protein powders was not flavor-dependent across crop types was located; this does not prove the claim false. While published risk assessments (such as Bandara et al., 2020) have evaluated Consumer Reports' data on heavy metals in protein powders, peer-reviewed scientific literature evaluating specific flavor-independence across crop types from those tests was not identified.

0:34:33unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

The Clean Label Project study found that cacao-based protein powders had elevated heavy metal levels due to the presence of cacao.

"Because it looked like at least in the Clean Label Project study that the cacao based were more had higher amounts of heavy metals due to cacao in there." (said at 0:34:33)

No published record matching the Clean Label Project study's specific findings on cacao-based protein powders and heavy metal contamination was located; this does not prove the claim false.

0:53:25needs contextmoderateThe Protein Mistakes Costing You Muscle in Midlife | Puori

Consuming protein immediately post-workout takes advantage of an enhanced muscle protein synthesis window (anabolic window) stimulated by resistance training.

"straight after training where you might actually have a higher muscle protein synthesis window or more open window after workout, right?" (said at 0:53:25)

Resistance training does stimulate muscle protein synthesis (MPS) and increases muscle sensitivity to amino acid ingestion, but the notion of an urgent, narrow 'anabolic window' requiring protein consumption straight after a workout requires substantial qualification. A meta-analysis of randomized controlled trials examining protein timing found that when controlling for total daily protein intake, consuming protein immediately pre- or post-workout did not significantly increase muscle strength or hypertrophy compared to other timing strategies. The heightened anabolic response to resistance training persists for many hours, making total daily protein intake and evenly spaced distributions the primary drivers of long-term muscular adaptation.

1:00:32unverifiedvery lowThe Protein Mistakes Costing You Muscle in Midlife | Puori

Genetically modified (GMO) crops are not permitted or cultivated in Denmark.

"And in Denmark you will never find GMO crops. They just don't allow it. We just don't allow it." (said at 1:00:32)

No published record matching the claim that genetically modified crops are prohibited or not permitted in Denmark was located; this does not prove the claim false.

1:01:18supportedmoderateThe Protein Mistakes Costing You Muscle in Midlife | Puori

European regulations require significantly more safety documentation before a new chemical, pesticide, or herbicide can be introduced to the market compared to US regulations.

"the way that you have to have way more documentation before you add a new chemical to the market or a new kind of pesticide or herbicide and so on." (said at 1:01:18)

Comparative regulatory analyses support the claim that European chemical safety regulations place greater requirements on manufacturers for pre-market safety documentation and demonstrating safety compared to traditional US regulatory frameworks under the Toxic Substances Control Act (TSCA). Under the European Union's REACH regulation (Regulation EC No 1907/2006), a precautionary regulatory framework mandates that chemical manufacturers and importers provide extensive toxicity and safety documentation to demonstrate safety prior to commercialization. Comparative policy analyses highlight that REACH explicitly shifts the legal burden to industry to produce safety data, contrasting with US approaches under TSCA where regulatory authorities faced greater burdens to establish potential risk before requesting comprehensive safety testing.

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