Roger Seheult
MedCram Videos
Roger Seheult is a physician, educator, and co-founder of MedCram Videos who has treated patients during the COVID-19 pandemic. His published research includes cost-effectiveness evaluations of vilobelimab for mechanically ventilated COVID-19 patients. Additionally, his work has examined the physiological effects of prophylactic bosentan on pulmonary artery pressure and exercise capacity at high altitude.
49 claims checked on air: 3 context 3 contradicted 2 overstated 33 supported 8 unverified 5 flagged
What they said on air - contradicted
Hospitalized patients with COVID-19 were found to have significantly lower 25-hydroxyvitamin D levels than symptomatic patients hospitalized with similar symptoms who tested negative for SARS-CoV-2.
"We see people being admitted to the hospital had lower rates than those that had similar symptoms but were not SARS-CoV-2 positive." (said at 0:25:40)
Observational research directly evaluating hospitalized COVID-19 patients alongside hospitalized symptomatic controls who tested negative for SARS-CoV-2 found no statistically significant difference in serum 25-hydroxyvitamin D levels between the two groups.
Heating human subjects in a 39°C water bath elevates interferon and TNF levels, and monocytes exposed to LPS produced 10 times higher interferon at 39°C compared to lower temperatures.
"And what they found was that they were able to independently of of these uh potential mutations that fever or or temperature itself was able to cause a secretion, an elevation in interferon, tumor necrosis factor, those sorts of things. There's one study that they did where they took subjects, put them in hot water baths at at various degrees... interferon levels were 10 times higher once they got up to about 39° uh centigrade" (said at 1:21:20)
The claim asserts that immersing human subjects in a hot water bath to reach ~39°C elevates interferon (IFN) and tumor necrosis factor (TNF) by up to 10-fold. In controlled human experimental trials examining hot water bath hyperthermia (e.g., raising core temperature to 39.5°C), hyperthermia did not significantly elevate ex vivo production of interferon-gamma or TNF-beta from stimulated blood mononuclear cells. Furthermore, in vitro studies of human mononuclear cells cultured at febrile temperatures (e.g., 39–40°C) generally demonstrate modest or suppressed 24-hour accumulation of TNF-alpha and fail to show a 10-fold increase in interferon secretion.
In the cell, mRNA remains in the cytoplasm and does not enter the nucleus.
"mRNA is in the cytoplasm of the cell. It's not in the nucleus of the cell." (said at 1:47:24)
In eukaryotic cells, messenger RNA (mRNA) is transcribed from DNA and undergoes essential processing steps—such as 5' capping, splicing, and assembly into messenger ribonucleoprotein complexes—within the nucleus before being exported across the nuclear pore complex into the cytoplasm for translation. The assertion that mRNA is not in the nucleus of the cell is contradicted by standard eukaryotic cell biology.
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