Roger Seheult
MedCram Videos
Roger Seheult is a physician, educator, and co-founder of MedCram Videos who has treated patients during the COVID-19 pandemic. His published research includes cost-effectiveness evaluations of vilobelimab for mechanically ventilated COVID-19 patients. Additionally, his work has examined the physiological effects of prophylactic bosentan on pulmonary artery pressure and exercise capacity at high altitude.
49 claims checked on air: 3 context 3 contradicted 2 overstated 33 supported 8 unverified 5 flagged
What they said on air - overstated
A British Medical Journal meta-analysis by Martineau and colleagues showed that vitamin D supplementation significantly reduced acute respiratory tract infections by 50%.
"Martineau, who is the uh the lead author on that British Medical Journal uh meta-analysis that was done a number of years ago now, showed that supplementation with vitamin D decreased acute chest infections by 50% significantly uh in in that study." (said at 0:22:24)
The 2017 BMJ individual participant data meta-analysis by Martineau and colleagues (25 randomized controlled trials, 10,933 participants) found that vitamin D supplementation significantly reduced the overall risk of acute respiratory tract infections, but by approximately 12% across all participants (adjusted odds ratio [aOR] 0.88, 95% CI 0.81 to 0.96), not 50%. Substantial reductions were observed only in specific subgroups: participants receiving daily or weekly dosing who were severely vitamin D deficient (baseline 25-hydroxyvitamin D < 25 nmol/L) experienced a 70% reduction (aOR 0.30, 95% CI 0.17 to 0.53), whereas bolus dosing showed no statistically significant benefit.
The Irish Longitudinal Study on Ageing (TILDA) showed that vitamin D supplementation provided health benefits.
"Also in the the longer aging uh health study called TILDA in in Ireland showed that uh vitamin D supplementation was beneficial." (said at 0:22:34)
The Irish Longitudinal Study on Ageing (TILDA) is an observational prospective cohort study of community-dwelling older adults in Ireland. Data from TILDA established that low blood serum 25-hydroxyvitamin D levels (vitamin D deficiency) were associated with adverse health markers and outcomes, including increased risk of incident depression, elevated C-reactive protein (inflammation), and higher risk of incident prediabetes. TILDA also confirmed that vitamin D supplement users had higher serum vitamin D levels. However, as an observational cohort study rather than an interventional clinical trial, TILDA demonstrated observational associations with serum vitamin D status rather than directly testing or proving the therapeutic health benefits of vitamin D supplementation.
- supports: The Prevalence of Vitamin D Deficiency and the Determinants of 25(OH)D Concentration in Ol… (The journals of gerontology. Series A, Biological sciences and medical sciences 2018) · cited 92x in the literature
"The main predictors (p < .05) of 25(OH)D concentration were supplement use (coefficient nmol/L: 27.2 [95% CI: 15.3-39.2])" (abstract, results, passage verified)
pubmedfull study (doi) - context: Vitamin D Deficiency Is Associated With an Increased Likelihood of Incident Depression in … (Journal of the American Medical Directors Association 2019) · cited 61x in the literature
"This study demonstrates that vitamin D deficiency is associated with a significant increase in the likelihood of developing depression in later life." (abstract, conclusions, passage verified)
pubmedfull study (doi) - context: Association between vitamin D deficiency and the risk of prevalent type 2 diabetes and inc… (EClinicalMedicine 2022) · cited 37x in the literature
"In longitudinal analyses evaluating diabetes status 4 years later, there was a 62% increased likelihood (RRR: 1·62, 95% CI: 1·12, 2·35; p = 0·011) of developing prediabetes for those with vitamin D <30 nmol/L compared to those with ≥75 nmol/L." (abstract, results, passage verified)
pubmedfull study (doi) - context: Vitamin D status & associations with inflammation in older adults. (PloS one 2023) · cited 16x in the literature
"In conclusion older adults with deficient vitamin D status had higher levels of inflammation as measured by CRP." (abstract, conclusions, passage verified)
pubmedfull study (doi)
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