Susan Magsamen
Susan Magsamen is a researcher whose work centers on neuroaesthetics, neuroscience, and public health. Her published research examines the impact of arts- and music-based interventions on mental health, trauma recovery, and youth well-being. She has also authored papers on translating neuroscience into educational practices and the effects of environmental settings on psychedelic therapies.
9 claims checked on air: 1 context 3 overstated 4 supported 1 unverified
What they said on air - overstated
Aesthetic experiences and engaging with art promote myelination enhancements in neural pathways.
"the myelination um enhancements that happen, too. So, creating this ability for for neural pathways to work better is is such a protective um attribute for us." (said at 0:16:07)
Broad claims that aesthetic experiences and general engagement with art enhance neural pathway myelination extrapolate heavily from specialized skill-learning literature. While intensive motor or auditory training (such as instrument practice or music-cued motor learning) can induce white matter microstructural changes on diffusion tensor imaging consistent with activity-dependent myelination, long-term developmental studies find that baseline white matter myelination trajectories proceed primarily via natural maturation regardless of musical expertise. Furthermore, direct evidence demonstrating that passive aesthetic experiences or general art appreciation induce de novo myelination in humans is lacking.
- partial: Diffusion tensor MRI tractography reveals increased fractional anisotropy (FA) in arcuate … (Brain and cognition 2017) · cited 64x in the literature
"Results revealed that FA increased significantly in the right arcuate fasciculus of the Music group only, as hypothesised, with trends for AD to increase and RD to decrease, a pattern of results consistent with activity-dependent increases in myelination." (abstract, results, passage verified)
pubmedfull study (doi) - contradicts: Neuroanatomical Disposition, Natural Development, and Training-Induced Plasticity of the H… (The Journal of neuroscience : the official journal of the Society for Neuroscience 2023) · cited 31x in the literature
"Maturational plasticity led to a continuous increase in white matter myelination and systematic changes of the auditory evoked P1-N1-P2 complex (decreasing latencies, synchronization effects between hemispheres, and amplitude changes) regardless of musical expertise." (abstract, results, passage verified)
pubmedfull study (doi)
Research by Assal Habibi at the University of Southern California demonstrated that arts/music training alters brain structure and increases brain mass.
"we've also seen some beautiful work by Assal Habibi from University of Southern California looking at literally changing brain structure and brain mass." (said at 0:16:32)
Assal Habibi and colleagues at the University of Southern California (Brain and Creativity Institute) have conducted longitudinal neuroimaging studies tracking children enrolled in systematic music training compared to sports and non-training control groups. Their research demonstrated that childhood music training induces regional structural plasticity—specifically altering the trajectory of cortical thickness maturation in auditory association areas (such as the posterior superior temporal gyrus) and increasing fractional anisotropy in white matter tracts of the corpus callosum. However, the studies demonstrated localized cortical and microstructural neurodevelopmental changes rather than an increase in overall 'brain mass.'
- partial: Childhood Music Training Induces Change in Micro and Macroscopic Brain Structure: Results … (Cerebral cortex (New York, N.Y. : 1991) 2018) · cited 193x in the literature
"Two years later we observed that children in the music group showed (1) a different rate of cortical thickness maturation between the right and left posterior superior temporal gyrus, and (2) higher fractional anisotropy in the corpus callosum, specifically in the crossing pathways connecting superior frontal, sensory, and motor segments. We conclude that music training induces macro and microstructural brain changes in school-age children, and that those changes are not attributable to pre-existing biological traits." (abstract, results, passage verified)
pubmedfull study (doi) - partial: Changes in auditory cortical thickness following music training in children: converging lo… (Brain structure & function 2020) · cited 21x in the literature
"We found that children in the music group showed a strong trend of lower rate of cortical thinning in the right posterior superior temporal gyrus. Together, our results provide evidence that music training induces structural brain changes in school-age children and that these changes are predominantly pronounced in the right auditory association areas." (abstract, results, passage verified)
pubmedfull study (doi)
Music and sound effectively reduce amygdala activation in the brain.
"music and sound are are really very effective in reducing amygdala activation and I think in large part because it's so so immediate, right?" (said at 0:21:12)
Functional neuroimaging research shows that music and auditory stimuli do not simply or universally reduce amygdala activity. Instead, music robustly modulates and frequently activates the amygdala depending on acoustic features, hedonic valence, tension, and emotional content. Meta-analyses of fMRI studies demonstrate significant amygdala activation during both pleasant and unpleasant music processing, with unpleasant or dissonant music evoking strong amygdala responses. While soothing music and therapeutic sound interventions have been hypothesized or observed to help downregulate hyperactive stress circuits and amygdala reactivity in specific contexts (such as anxiety or trauma recovery), characterizing music and sound broadly as an immediate down-regulator of amygdala activation oversimplifies and overstates the bidirectional, valence-dependent engagement of the amygdala by auditory stimuli.
- contradicts: Investigating emotion with music: an fMRI study. (Human brain mapping 2006) · cited 1051x in the literature
"Unpleasant (permanently dissonant) music contrasted with pleasant (consonant) music showed activations of amygdala, hippocampus, parahippocampal gyrus, and temporal poles." (abstract, results, passage verified)
pubmedfull study (doi) - context: A Neurobiological Framework for the Therapeutic Potential of Music and Sound Interventions… (International journal of environmental research and public health 2022) · cited 35x in the literature
"Despite the lack of music interventions for ICU survivors, music has the potential to help people suffering from PTSD by decreasing amygdala activity, improving hippocampal and prefrontal brain function, and balancing the HPA-axis." (abstract, conclusions, passage verified)
pubmedfull study (doi) - contradicts: On joy and sorrow: Neuroimaging meta-analyses of music-induced emotion. (Imaging neuroscience (Cambridge, Mass.) 2025) · cited 12x in the literature
"Our results revealed the activation of a range of cortical and subcortical regions, including the amygdala, insula, striatum, thalamus, hippocampus, anterior cingulate gyrus, and superior temporal gyrus. Moreover, our findings indicated that certain regions were specifically activated based on the hedonic valence and arousal of the stimuli. Particularly, whereas the anterior cingulate cortex (ACC), dorsal striatum, and thalamus were dependent on arousal effects, amygdala activation was dependent on hedonic valence." (abstract, results, passage verified)
pubmedfull study (doi)
Fact-checked episodes
Publications